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C5 蛋白

(Complement Component 5 (C5))
The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis. [provided by RefSeq, Jul 2008].

20 results :

C5 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274038
 
C5 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320495
 
C5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
产品编号 ABIN1347565
 
C5 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN7013368
 
C5 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN6809857
 
C5 宿主: 大鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN6809876
 
C5 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
产品编号 ABIN6938883
 
C5 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant WB, SDS, ELISA
产品编号 ABIN7575245
 
C5 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant WB, SDS, ELISA
产品编号 ABIN7575244
 
C5 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant WB, SDS, ELISA
产品编号 ABIN7580402
 
C5 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant >90 % as determined by SDS-PAGE. WB, SDS, Imm, ELISA, AcA Active
产品编号 ABIN7607266
 
C5 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % WB, SDS, Imm, PC
产品编号 ABIN7422781
 
C5 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC
产品编号 ABIN7395452
 
C5 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % WB, SDS, Imm, PC
产品编号 ABIN7395455
 
C5 宿主: 兔 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
产品编号 ABIN6952281
 
C5 宿主: Pig 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN7478993
 
C5 宿主: Cow 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN7583699
 
C5 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN7583700
 
C5 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant WB, SDS
产品编号 ABIN6120499
 
C5 宿主: 人 宿主: HEK-293 Cells Recombinant 95,00 %
产品编号 ABIN7316821
 
  • 类型 Protein
    • Protein
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Activity Assay (AcA)
    • Affinity Purification (AP)
    • Antibody Array (AA)
  • 适用
    • Human
    • Mouse
    • Rat
    • Cow
    • Cynomolgus
    • Pig
    • Rabbit
  • 图像
  • Carrier free only
  • 抗体来源
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Yeast
    • Wheat germ
  • 抗原表位
    • AA 19-1676
    • AA 1-74
    • AA 679-755
    • AA 1-77
    • AA 1541-1688
    • AA 1550-1661
    • AA 19-1678
    • AA 19-1680
    • AA 19-350
    • AA 24-1688
    • full length
  • 标记
    • His tag
    • 非结合性
    • GST tag
    • Biotin,His-Avi Tag
    • His-SUMO Tag
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • 生物活性
    • Biologically Active
  • Supplier
    • antibodies-online
    • ACROBiosystems
    • CUSABIO
    • Abbexa

Latest Publications for our C5 蛋白

Seow, Lim, Iyer, Suen, Ariffin, Hohenhaus, Sweet, Fairlie: "Inflammatory responses induced by lipopolysaccharide are amplified in primary human monocytes but suppressed in macrophages by complement protein C5a." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 8, pp. 4308-16, (2013) (PubMed).

Aliases for C5 蛋白

complement C5 (C5) 蛋白
complement component 5 (c5) 蛋白
complement component 5 (C5) 蛋白
hemolytic complement (Hc) 蛋白
C5 蛋白
C5a 蛋白
C5b 蛋白
CPAMD4 蛋白
Hc 蛋白
He 蛋白
LOC565774 蛋白
RGD1561905 蛋白
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