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C4BPB 产品

(Complement Component 4 Binding Protein, beta (C4BPB))

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This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq, Jul 2008].

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Featured C4BPB Categories

C4BPB 抗体

High quality antibodies with extensive validation data.

C4BPB ELISA试剂盒

Reliable ELISA kits for a wide range of species.

C4BPB 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended C4BPB 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IP
Validations
  • (1)
  • (3)
Cat. No. ABIN513876
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (3)
Cat. No. ABIN7011062
Quantity 60 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, IP
Validations
  • (3)
Cat. No. ABIN7146168
Quantity 100 μL
Datasheet Datasheet

Recommended C4BPB ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962013
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965287
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955009
Quantity 96 tests
Datasheet Datasheet

Recommended C4BPB 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1347544
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7391957
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN3090393
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our C4BPB Products

Jiang, Shi, Wei, Li, Yang, Wang, Liu, Chen, Tu, Li, Li: "Serum amyloid A, protein Z, and C4b-binding protein β chain as new potential biomarkers for pulmonary tuberculosis." in: PLoS ONE, Vol. 12, Issue 3, pp. e0173304, (2017) (PubMed).

Shimotahira, Oogai, Kawada-Matsuo, Yamada, Fukutsuji, Nagano, Yoshimura, Noguchi, Komatsuzawa: "The surface layer of Tannerella forsythia contributes to serum resistance and oral bacterial coaggregation." in: Infection and immunity, Vol. 81, Issue 4, pp. 1198-206, (2013) (PubMed).

Wells, Burgess, Nisbet: "Characterization of the ovine complement 4 binding protein-beta (C4BPB) chain as a serum biomarker for enhanced diagnosis of sheep scab." in: Molecular and cellular probes, Vol. 27, Issue 3-4, pp. 158-63, (2013) (PubMed).

Emery, Erdman, Bowen, Newton, Winchell, Meyer, Tong, Cook, Holloway, McCaustland, Rota, Bankamp, Lowe, Ksiazek, Bellini, Anderson: "Real-time reverse transcription-polymerase chain reaction assay for SARS-associated coronavirus." in: Emerging infectious diseases, Vol. 10, Issue 2, pp. 311-6, (2004) (PubMed).

Synonyms and alternative names related to C4BPB

complement component 4 binding protein beta (C4BPB), complement component 4 binding protein, beta (C4bpb), C4BP, C4bp-ps1, C4BPB

Protein level used designations for C4BPB

  • complement component 4 binding protein, beta
  • complement component 4 binding protein, beta chain
  • C4b-binding protein beta chain
  • complement component 4-binding protein, beta
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