C4B 抗体
(Complement Component C4b (C4b))
This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. [provided by RefSeq, Jul 2008].
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C4B 抗体 by 适用
Find C4B 抗体 for a variety of species such as anti-Human C4B, anti-Mouse C4B, anti-Dog C4B. The species listed below are among those available. Click on a link to go to the corresponding products.
C4B 抗体 by 抗体来源
Find C4B 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
C4B 抗体 by 克隆形成能力
Find available monoclonal or polyclonal C4B 抗体. Click on a link to go to the corresponding products.
C4B 抗体 by 克隆
Find C4B 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular C4B 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
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Cat. No.
ABIN7433423
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7433420
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (3)
Cat. No.
ABIN513870
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (1)
Cat. No.
ABIN7445822
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7148365
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IHC, IF, StM
Validations
- (1)
Cat. No.
ABIN6940809
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN3030240
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No.
ABIN1713472
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN1699970
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN1692703
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN1698157
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN5000360
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN1694516
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN5000361
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN1696346
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our C4B 抗体
: "Anti-TCRβ mAb induces long-term allograft survival by reducing antigen-reactive T cells and sparing regulatory T cells." in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, Vol. 12, Issue 6, pp. 1409-18, (2012) (PubMed).: "Synergistic deposition of C4d by complement-activating and non-activating antibodies in cardiac transplants." in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, Vol. 7, Issue 11, pp. 2605-14, (2007) (PubMed).
: "Allograft rejection requires STAT5a/b-regulated antiapoptotic activity in T cells but not B cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 1, pp. 128-37, (2005) (PubMed).
: "Macrophage-derived complement component C4 can restore humoral immunity in C4-deficient mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 10, pp. 5489-95, (2002) (PubMed).
: "Anti-DNA autoreactivity in C4-deficient mice." in: European journal of immunology, Vol. 32, Issue 9, pp. 2672-9, (2002) (PubMed).
: "Monoclonal antibodies to complement components without the need of their prior purification. II. Antibodies to mouse C3 and C4." in: Hybridoma, Vol. 9, Issue 4, pp. 309-17, (1990) (PubMed).
Aliases for C4B 抗体
complement C4B (Chido blood group) (C4B) 抗体complement C4A (Rodgers blood group) (C4A) 抗体
complement component 4 (c4) 抗体
complement C4-B (LOC462577) 抗体
complement component 4B (Chido blood group) (C4B) 抗体
complement component 4A (Rodgers blood group) (C4a) 抗体
complement component 4B (Chido blood group) (C4b) 抗体
complement C4B (Chido blood group) (C4b) 抗体
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