C1q 抗体
(Complement Fragment C1q (C1q))
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
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Latest Publications for our C1q 抗体
: "Selectivity analysis of single binder assays used in plasma protein profiling." in: Proteomics, Vol. 13, Issue 23-24, pp. 3406-10, (2013) (PubMed).: "Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model." in: Proteome science, Vol. 9, pp. 73, (2011) (PubMed).
: "Complement protein C1q forms a complex with cytotoxic prion protein oligomers." in: The Journal of biological chemistry, Vol. 285, Issue 25, pp. 19267-76, (2010) (PubMed).
: "Therapeutic targeting of classical and lectin pathways of complement protects from ischemia-reperfusion-induced renal damage." in: The American journal of pathology, Vol. 176, Issue 4, pp. 1648-59, (2010) (PubMed).
: "B cells produce pathogenic antibodies and impair recovery after spinal cord injury in mice." in: The Journal of clinical investigation, Vol. 119, Issue 10, pp. 2990-9, (2009) (PubMed).
: "Genomic assessment of a multikinase inhibitor, sorafenib, in a rodent model of pulmonary hypertension." in: Physiological genomics, Vol. 33, Issue 2, pp. 278-91, (2008) (PubMed).
: "Antibody ligation of murine Ly-6G induces neutropenia, blood flow cessation, and death via complement-dependent and independent mechanisms." in: Journal of leukocyte biology, Vol. 85, Issue 1, pp. 55-63, (2008) (PubMed).
: "Development of a humanized C1q A chain knock-in mouse: assessment of antibody independent beta-amyloid induced complement activation." in: Molecular immunology, Vol. 45, Issue 11, pp. 3244-52, (2008) (PubMed).
: "Highly specific inhibition of C1q globular-head binding to human IgG: a novel approach to control and regulate the classical complement pathway using an engineered single chain antibody variable ..." in: Molecular immunology, Vol. 45, Issue 9, pp. 2570-80, (2008) (PubMed).
: "A dominant complement fixation pathway for pneumococcal polysaccharides initiated by SIGN-R1 interacting with C1q." in: Cell, Vol. 125, Issue 1, pp. 47-58, (2006) (PubMed).
Aliases for C1q 抗体
complement component 1, q subcomponent, alpha polypeptide (C1qa) 抗体AI255395 抗体
C1q 抗体
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