C-Type Lectin Domain Family 6, Member A Antibodies

Binds high-mannose carbohydrates in a Ca(2+)-dependent manner. Functionnal receptor for alpha-mannans on C. albicans hypheas. Plays an important role in the host defense against C. albicans infection by inducing TH17 cell differentiation. Recognizes also, in a manose dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptative immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G and Syk-CARD9-NF-kappa-B-dependent pathway.

Latest Publications for our C-Type Lectin Domain Family 6, Member A 抗体

Botting, Bertram, Baharlou, Sandgren, Fletcher, Rhodes, Rana, Plasto, Wang, Lim, Barnouti, Kohout, Papadopoulos, Merten, Olbourne, Cunningham, Haniffa, Harman: "Phenotypic and functional consequences of different isolation protocols on skin mononuclear phagocytes." in: Journal of leukocyte biology, Vol. 101, Issue 6, pp. 1393-1403, (2017) (PubMed).

Brasch, Mörig, Neumann, Proksch: "Expression of antimicrobial peptides and toll-like receptors is increased in tinea and pityriasis versicolor." in: Mycoses, Vol. 57, Issue 3, pp. 147-52, (2014) (PubMed).

Barrett, Rahman, Fernandez, Parsons, Xing, Austen, Kanaoka: "Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes." in: The Journal of experimental medicine, Vol. 208, Issue 3, pp. 593-604, (2011) (PubMed).

Gringhuis, Wevers, Kaptein, van Capel, Theelen, Boekhout, de Jong, Geijtenbeek: "Selective C-Rel activation via Malt1 controls anti-fungal T(H)-17 immunity by dectin-1 and dectin-2." in: PLoS pathogens, Vol. 7, Issue 1, pp. e1001259, (2011) (PubMed).

Suram, Gangelhoff, Taylor, Rosas, Brown, Bonventre, Akira, Uematsu, Williams, Murphy, Leslie: "Pathways regulating cytosolic phospholipase A2 activation and eicosanoid production in macrophages by Candida albicans." in: The Journal of biological chemistry, Vol. 285, Issue 40, pp. 30676-85, (2010) (PubMed).

Taylor, Reid, Heinsbroek, Brown, Gordon, Wong: "Dectin-2 is predominantly myeloid restricted and exhibits unique activation-dependent expression on maturing inflammatory monocytes elicited in vivo." in: European journal of immunology, Vol. 35, Issue 7, pp. 2163-74, (2005) (PubMed).

Aliases for C-Type Lectin Domain Family 6, Member A 抗体

C-type lectin domain containing 6A (CLEC6A) 抗体
C-type lectin domain family 6, member A (Clec6a) 抗体
CLEC4N 抗体
CLEC6A 抗体
CLECSF10 抗体

C-Type Lectin Domain Family 6, Member A 抗体

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Latest Publications for our C-Type Lectin Domain Family 6, Member A 抗体

Aliases for C-Type Lectin Domain Family 6, Member A 抗体

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