Caspase 9 蛋白
(Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1\; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms. [provided by RefSeq, Jul 2008].
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12 results
CASP9
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 95 % by SDS-PAGE gel analyses
WB, ELISA
1 image
CASP9
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
WB, SDS, Imm, PC
CASP9
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
WB, SDS, Imm, PC
CASP9
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
WB, SDS, Imm, PC
CASP9
宿主: 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 97 %
WB, SDS, Imm, PC
CASP9
宿主: 大鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
WB, SDS, Imm, PC
CASP9
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Latest Publications for our Caspase 9 蛋白
: "A Complex between Atg7 and Caspase-9: A NOVEL MECHANISM OF CROSS-REGULATION BETWEEN AUTOPHAGY AND APOPTOSIS." in: The Journal of biological chemistry, Vol. 289, Issue 10, pp. 6485-97, (2014) (PubMed).: "Differential regulation of c-Jun protein plays an instrumental role in chemoresistance of cancer cells." in: The Journal of biological chemistry, Vol. 288, Issue 27, pp. 19321-9, (2013) (PubMed).
: "Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34337-47, (2010) (PubMed).
: "Neuregulin-1 attenuated doxorubicin-induced decrease in cardiac troponins." in: American journal of physiology. Heart and circulatory physiology, Vol. 297, Issue 6, pp. H1974-83, (2009) (PubMed).
: "Caspase-10-mediated heat shock protein 90 beta cleavage promotes UVB irradiation-induced cell apoptosis." in: Molecular and cellular biology, Vol. 29, Issue 13, pp. 3657-64, (2009) (PubMed).
: "A novel natural compound, a cycloanthranilylproline derivative (Fuligocandin B), sensitizes leukemia cells to apoptosis induced by tumor necrosis factor related apoptosis-inducing ligand (TRAIL) ..." in: Blood, Vol. 110, Issue 5, pp. 1664-74, (2007) (PubMed).
: "Proteolytic activation of protein kinase C-epsilon by caspase-mediated processing and transduction of antiapoptotic signals." in: The Journal of biological chemistry, Vol. 277, Issue 44, pp. 41850-6, (2002) (PubMed).
: "Gelsolin in complex with phosphatidylinositol 4,5-bisphosphate inhibits caspase-3 and -9 to retard apoptotic progression." in: The Journal of biological chemistry, Vol. 275, Issue 6, pp. 3761-6, (2000) (PubMed).
Aliases for Caspase 9 蛋白
caspase 9 (CASP9) 蛋白caspase 9 (Casp9) 蛋白
AI115399 蛋白
APAF-3 蛋白
Apaf3 蛋白
APAF3 蛋白
AW493809 蛋白
CASP-9 蛋白
Casp-9-CTD 蛋白
CASP9 蛋白
Casp9_v1 蛋白
Caspase-9 蛋白
ICE-LAP6 蛋白
Ice-Lap6 蛋白
Mch6 蛋白
MCH6 蛋白
PPP1R56 蛋白
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