The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].
Li, Ma, Wang, Zeng, Li, Kang, Hao: "Exosomal microRNA-141 is upregulated in the serum of prostate cancer patients." in: OncoTargets and therapy, Vol. 9, pp. 139-48, (2016) (PubMed).