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CARD9 产品

(Caspase Recruitment Domain Family, Member 9 (CARD9))

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The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined. [provided by RefSeq, Jul 2008].

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Featured CARD9 Categories

CARD9 抗体

High quality antibodies with extensive validation data.

CARD9 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

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Recommended CARD9 蛋白

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Latest Publications for our CARD9 Products

Gavino, Hamel, Zeng, Legault, Guiot, Chankowsky, Lejtenyi, Lemire, Alarie, Dufresne, Boursiquot, McIntosh, Langelier, Behr, Sheppard, Foulkes, Vinh: "Impaired RASGRF1/ERK-mediated GM-CSF response characterizes CARD9 deficiency in French-Canadians." in: The Journal of allergy and clinical immunology, Vol. 137, Issue 4, pp. 1178-1188.e7, (2016) (PubMed).

Bertin, Guo, Wang, Srinivasula, Jacobson, Poyet, Merriam, Du, Dyer, Robison, DiStefano, Alnemri: "CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-kappa B." in: The Journal of biological chemistry, Vol. 275, Issue 52, pp. 41082-6, (2001) (PubMed).

Chen, Ghilardi, Wang, Baker, Xie, Gurney, Grewal, de Sauvage: "Development of Th1-type immune responses requires the type I cytokine receptor TCCR." in: Nature, Vol. 407, Issue 6806, pp. 916-20, (2000) (PubMed).

Sprecher, Grant, Baumgartner, Presnell, Schrader, Yamagiwa, Whitmore, OHara, Foster: "Cloning and characterization of a novel class I cytokine receptor." in: Biochemical and biophysical research communications, Vol. 246, Issue 1, pp. 82-90, (1998) (PubMed).

Synonyms and alternative names related to CARD9

caspase recruitment domain family, member 9 (Card9), caspase recruitment domain family member 9 (CARD9), caspase recruitment domain family, member 9 (card9), caspase recruitment domain family member 9 (card9), CANDF2, card9, Gm782, hCARD9

Protein level used designations for CARD9

  • caspase recruitment domain-containing protein 9
  • Caspase recruitment domain-containing protein 9
  • caspase recruitment domain family, member 9
  • caspase recruitment domain protein 9
  • caspase recruitment domain-containing protein 9-like
  • rCARD9
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