CARD11 抗体
(Caspase Recruitment Domain Family, Member 11 (CARD11))
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008].
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Latest Publications for our CARD11 抗体
: "Phosphorylation of Carma1, but not Bcl10, by Akt regulates TCR/CD28-mediated NF-κB induction and cytokine production." in: Molecular immunology, Vol. 59, Issue 1, pp. 110-6, (2014) (PubMed).: "T cell receptor-dependent activation of mTOR signaling in T cells is mediated by Carma1 and MALT1, but not Bcl10." in: Science signaling, Vol. 7, Issue 329, pp. ra55, (2014) (PubMed).
: "Signaling by Fyn-ADAP via the Carma1-Bcl-10-MAP3K7 signalosome exclusively regulates inflammatory cytokine production in NK cells." in: Nature immunology, Vol. 14, Issue 11, pp. 1127-36, (2013) (PubMed).
: "MAGUK-controlled ubiquitination of CARMA1 modulates lymphocyte NF-kappaB activity." in: Molecular and cellular biology, Vol. 30, Issue 4, pp. 922-34, (2010) (PubMed).
: "Bcl10 controls TCR- and FcgammaR-induced actin polymerization." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 7, pp. 4373-84, (2007) (PubMed).
: "Regulation of NF-kappaB activation in T cells via association of the adapter proteins ADAP and CARMA1." in: Science (New York, N.Y.), Vol. 316, Issue 5825, pp. 754-8, (2007) (PubMed).
: "MALT1 and the API2-MALT1 fusion act between CD40 and IKK and confer NF-kappa B-dependent proliferative advantage and resistance against FAS-induced cell death in B cells." in: Blood, Vol. 105, Issue 7, pp. 2891-9, (2005) (PubMed).
: "Phosphorylation of the CARMA1 linker controls NF-kappaB activation." in: Immunity, Vol. 23, Issue 6, pp. 561-74, (2005) (PubMed).
: "Overexpression of caspase recruitment domain (CARD) membrane-associated guanylate kinase 1 (CARMA1) and CARD9 in primary gastric B-cell lymphoma." in: Cancer, Vol. 104, Issue 9, pp. 1885-93, (2005) (PubMed).
: "CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-kappa B activation." in: Nature immunology, Vol. 3, Issue 9, pp. 836-43, (2002) (PubMed).
Aliases for CARD11 抗体
caspase recruitment domain family member 11 (CARD11) 抗体caspase recruitment domain family, member 11 (Card11) 抗体
caspase recruitment domain-containing protein 11 (LOC100550812) 抗体
caspase recruitment domain family member 11 (card11) 抗体
caspase recruitment domain family member 11 (Card11) 抗体
0610008L17Rik 抗体
2410011D02Rik 抗体
BENTA 抗体
BIMP3 抗体
CARD11 抗体
CARMA1 抗体
LOC100232755 抗体
PPBL 抗体
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