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CARD11 抗体 (AA 10-59)

This 兔 多克隆 antibody specifically detects CARD11 in WB, IHC, ELISA 和 IF. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN1534305
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CARD11 抗体 (AA 10-59) (ABIN1534305)

抗原

See all CARD11 抗体
CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

适用

  • 45
  • 21
  • 4
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 43
  • 1
  • 1
兔

克隆类型

  • 33
  • 12
多克隆

标记

  • 29
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This CARD11 antibody is un-conjugated

应用范围

  • 37
  • 19
  • 13
  • 11
  • 7
  • 6
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 10-59

    原理

    CARD 11 Antibody

    特异性

    CARD 11 Polyclonal Antibody detects endogenous levels of CARD 11 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human CARD11. AA range:10-59

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

    别名

    CARD11

    背景

    Synonyms: CARD11, CARMA1, Caspase recruitment domain-containing protein 11, CARD-containing MAGUK protein 1, Carma 1

    Background: The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008],

    Gene Name: CARD11

    Protein Name: Caspase recruitment domain-containing protein 11

    分子量

    132 kDa

    基因ID

    84433

    OMIM

    607210

    UniProt

    Q9BXL7

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, BCR Signaling
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