(Caspase Recruitment Domain Family, Member 10 (CARD10))
The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB\; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM, Mar 2008].
Kahle, Gulbahce, Shaw, Lim, Hill, Barabási, Zoghbi: "Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia." in: Human molecular genetics, Vol. 20, Issue 3, pp. 510-27, (2011) (PubMed).
Martin, Galisteo, Gutkind et al.: "CXCL8/IL8 stimulates vascular endothelial growth factor (VEGF) expression and the autocrine activation of VEGFR2 in endothelial cells by activating NFkappaB through the CBM (Carma3/Bcl10/Malt1) ..." in: The Journal of biological chemistry, Vol. 284, Issue 10, pp. 6038-42, (2009) (PubMed).
Fischer, Tedford, Wirth: "New roles for Bcl10 in B-cell development and LPS response." in: Trends in immunology, Vol. 25, Issue 3, pp. 113-6, (2004) (PubMed).
Stilo, Liguoro, Di Jeso, Formisano, Consiglio, Leonardi, Vito: "Physical and functional interaction of CARMA1 and CARMA3 with Ikappa kinase gamma-NFkappaB essential modulator." in: The Journal of biological chemistry, Vol. 279, Issue 33, pp. 34323-31, (2004) (PubMed).
Fanning, Anderson: "Protein modules as organizers of membrane structure." in: Current opinion in cell biology, Vol. 11, Issue 4, pp. 432-9, (1999) (PubMed).
Aliases for CARD10 抗体
caspase recruitment domain family, member 10 (Card10) 抗体 caspase recruitment domain family member 10 (CARD10) 抗体 AI449026 抗体 BIMP1 抗体 Bimp1 抗体 CARD10 抗体 CARMA3 抗体 Carma3 抗体