The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family. This gene is a susceptibility locus for childhood absence epilepsy. [provided by RefSeq, Dec 2010].
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Kang, Chen, Felix, Letts, Frankel, Mori, Campbell: "Biochemical and biophysical evidence for gamma 2 subunit association with neuronal voltage-activated Ca2+ channels." in: The Journal of biological chemistry, Vol. 276, Issue 35, pp. 32917-24, (2001) (PubMed).