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CACNB2 产品

(Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))

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This gene encodes a subunit of a voltage-dependent calcium channel protein that is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome, an autoimmune disorder. Mutations in this gene are associated with Brugada syndrome. Alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Feb 2013].

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Featured CACNB2 Categories

CACNB2 抗体

High quality antibodies with extensive validation data.

CACNB2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CACNB2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (5)
Cat. No. ABIN560142
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
  • (4)
Cat. No. ABIN560146
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, IF, ICC, AA
Validations
  • (5)
Cat. No. ABIN2485040
Quantity 100 μg
Datasheet Datasheet

Recommended CACNB2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6213228
Quantity 96 tests
Datasheet Datasheet

Recommended CACNB2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1347832
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3125859
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3090129
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CACNB2 Products

Liu, Deng, Wang, Zhang, Luo, Yan, Su, Liu: "KCNE2 modulates cardiac L-type Ca(2+) channel." in: Journal of molecular and cellular cardiology, Vol. 72, pp. 208-18, (2014) (PubMed).

Scholten, Preisinger, Corradini, Bourgonje, Hennrich, van Veen, Swaminathan, Joiner, Vos, Anderson, Heck: "Phosphoproteomics study based on in vivo inhibition reveals sites of calmodulin-dependent protein kinase II regulation in the heart." in: Journal of the American Heart Association, Vol. 2, Issue 4, pp. e000318, (2013) (PubMed).

Horiuchi-Hirose, Kashihara, Nakada, Kurebayashi, Shimojo, Shibazaki, Sheng, Yano, Hirose, Hongo, Sakurai, Moriizumi, Ueda, Yamada: "Decrease in the density of t-tubular L-type Ca2+ channel currents in failing ventricular myocytes." in: American journal of physiology. Heart and circulatory physiology, Vol. 300, Issue 3, pp. H978-88, (2011) (PubMed).

Abiria, Colbran: "CaMKII associates with CaV1.2 L-type calcium channels via selected beta subunits to enhance regulatory phosphorylation." in: Journal of neurochemistry, Vol. 112, Issue 1, pp. 150-61, (2010) (PubMed).

Ortiz-Miranda, Dayanithi, Velázquez-Marrero, Custer, Treistman, Lemos: "Differential modulation of N-type calcium channels by micro-opioid receptors in oxytocinergic versus vasopressinergic neurohypophysial terminals." in: Journal of cellular physiology, Vol. 225, Issue 1, pp. 276-88, (2010) (PubMed).

Teng, Iida, Ito, Izumi-Nakaseko, Kojima, Adachi-Akahane, Iida: "Role of glycine residues highly conserved in the S2-S3 linkers of domains I and II of voltage-gated calcium channel alpha(1) subunits." in: Biochimica et biophysica acta, Vol. 1798, Issue 5, pp. 966-74, (2010) (PubMed).

Burashnikov, Pfeiffer, Barajas-Martinez, Delpón, Hu, Desai, Borggrefe, Häissaguerre, Kanter, Pollevick, Guerchicoff, Laiño, Marieb, Nademanee, Nam, Robles, Schimpf, Stapleton, Viskin, Winters et al.: "Mutations in the cardiac L-type calcium channel associated with inherited J-wave syndromes and sudden cardiac death. ..." in: Heart rhythm : the official journal of the Heart Rhythm Society, Vol. 7, Issue 12, pp. 1872-82, (2010) (PubMed).

Heneghan, Mitra-Ganguli, Stanish, Liu, Zhao, Rittenhouse: "The Ca2+ channel beta subunit determines whether stimulation of Gq-coupled receptors enhances or inhibits N current." in: The Journal of general physiology, Vol. 134, Issue 5, pp. 369-84, (2009) (PubMed).

Synonyms and alternative names related to CACNB2

calcium voltage-gated channel auxiliary subunit beta 2 (CACNB2), calcium channel, voltage-dependent, beta 2 subunit (Cacnb2), calcium voltage-gated channel auxiliary subunit beta 2 (Cacnb2), calcium channel, voltage-dependent, beta 2b (cacnb2b), AW060387, CAB2, Cacnb2, CACNB2, CACNB2.2, cacnb2a, CACNLB2, Cacnlb2, CAVB2, Cavbeta2, Cchb2, im:7141271, MYSB, si:dkey-32m20.2

Protein level used designations for CACNB2

  • CAB2
  • calcium channel voltage-dependent subunit beta 2
  • lambert-Eaton myasthenic syndrome antigen B
  • myasthenic (Lambert-Eaton) syndrome antigen B
  • voltage-dependent L-type calcium channel subunit beta-2
  • cardiac calcium channel beta subunit
  • cardiac calcium channel beta-subunit
  • calcium channel, voltage-dependent, beta 2 subunit
  • L-type calcium channel beta subunit
  • voltage-dependent L-type calcium channel subunit beta-2-like
  • CAB2a
  • calcium channel, voltage-dependent, beta 2b
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