Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that cleaves the '76-Gln-|-Phe-77' bond of synaptobrevin-2 (By similarity).
Latest Publications for our Botulinum Neurotoxin Type B 抗体
Jenko, Zhang, Kostenko, Fan, Garcia-Rodriguez, Lou, Marks, Varnum: "Development of an ELISA microarray assay for the sensitive and simultaneous detection of ten biodefense toxins." in: The Analyst, Vol. 139, Issue 20, pp. 5093-102, (2015) (PubMed).
Aliases for Botulinum Neurotoxin Type B 抗体
botulinum neurotoxin type B (boNT/B) 抗体 botulinum neurotoxin type B, BoNT/B (CLL_0038) 抗体