BIRC3 抗体
(Baculoviral IAP Repeat Containing 3 (BIRC3))
This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011].
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Latest Publications for our BIRC3 抗体
: "Prolonged lipopolysaccharide exposure induces transient immunosuppression in BV2 microglia." in: Journal of cellular physiology, Vol. 234, Issue 2, pp. 1889-1903, (2019) (PubMed).: "Cellular inhibitor of apoptosis protein 2 promotes the epithelial-mesenchymal transition in triple-negative breast cancer cells through activation of the AKT signaling pathway." in: Oncotarget, Vol. 8, Issue 45, pp. 78781-78795, (2018) (PubMed).
: "Perfluorodecanoic acid stimulates NLRP3 inflammasome assembly in gastric cells." in: Scientific reports, Vol. 7, pp. 45468, (2018) (PubMed).
: "Upregulated WDR5 promotes proliferation, self-renewal and chemoresistance in bladder cancer via mediating H3K4 trimethylation." in: Scientific reports, Vol. 5, pp. 8293, (2015) (PubMed).
: "Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer." in: Journal of bioenergetics and biomembranes, (2015) (PubMed).
: "Antibody validation by combining immunohistochemistry and protein extraction from formalin-fixed paraffin-embedded tissues." in: Histopathology, Vol. 60, Issue 6B, pp. E37-50, (2012) (PubMed).
: "Phase I trial of induction histone deacetylase and proteasome inhibition followed by surgery in non-small-cell lung cancer." in: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Vol. 7, Issue 11, pp. 1683-90, (2012) (PubMed).
: "Zoledronic acid directly suppresses cell proliferation and induces apoptosis in highly tumorigenic prostate and breast cancers." in: Journal of carcinogenesis, Vol. 10, pp. 2, (2011) (PubMed).
: "Hedgehog inhibition promotes a switch from Type II to Type I cell death receptor signaling in cancer cells." in: PLoS ONE, Vol. 6, Issue 3, pp. e18330, (2011) (PubMed).
: "Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation." in: Molecular cell, Vol. 38, Issue 1, pp. 101-13, (2010) (PubMed).
Aliases for BIRC3 抗体
baculoviral IAP repeat containing 3 (BIRC3) 抗体baculoviral IAP repeat-containing 3 (Birc3) 抗体
baculoviral IAP repeat-containing protein 3 (LOC100399118) 抗体
inhibitor of apoptosis protein-2 (OpmnVgp074) 抗体
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