BIRC2 抗体
(Baculoviral IAP Repeat Containing 2 (BIRC2))
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].
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Latest Publications for our BIRC2 抗体
: "Prolonged lipopolysaccharide exposure induces transient immunosuppression in BV2 microglia." in: Journal of cellular physiology, Vol. 234, Issue 2, pp. 1889-1903, (2019) (PubMed).: "IAPs cause resistance to TRAIL-dependent apoptosis in follicular thyroid cancer." in: Endocrine-related cancer, Vol. 25, Issue 3, pp. 295-308, (2019) (PubMed).
: "Anti-apoptotic protein BRE/BRCC45 attenuates apoptosis through maintaining the expression of caspase inhibitor XIAP in mouse Lewis lung carcinoma D122 cells." in: Apoptosis : an international journal on programmed cell death, Vol. 19, Issue 5, pp. 829-40, (2014) (PubMed).
: "Ischemic preconditioning reduces neurovascular damage after hypoxia-ischemia via the cellular inhibitor of apoptosis 1 in neonatal brain." in: Stroke; a journal of cerebral circulation, Vol. 44, Issue 1, pp. 162-9, (2012) (PubMed).
: "Reawakening the cellular death program in neoplasia through the therapeutic blockade of IAP function." in: The Journal of clinical investigation, Vol. 115, Issue 10, pp. 2673-8, (2005) (PubMed).
: "Expression and localization of inhibitor of apoptosis proteins in normal human tissues." in: Human pathology, Vol. 37, Issue 1, pp. 78-86, (2005) (PubMed).
: "The inhibitors of apoptosis: there is more to life than Bcl2." in: Oncogene, Vol. 22, Issue 53, pp. 8568-80, (2003) (PubMed).
: "TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2." in: Nature, Vol. 416, Issue 6878, pp. 345-7, (2002) (PubMed).
Aliases for BIRC2 抗体
baculoviral IAP repeat containing 2 (BIRC2) 抗体baculoviral IAP repeat-containing 2 (Birc2) 抗体
baculoviral IAP repeat containing 2 (birc2) 抗体
baculoviral IAP repeat containing 2 L homeolog (birc2.L) 抗体
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