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BIM 抗体

(BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jul 2008].

122 results :

BCL2L11 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7430234
 
BCL2L11 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
Pubmed 2 references
产品编号 ABIN682873
 
BCL2L11 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7145302
 
BCL2L11 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22105 unconjugated
产品编号 ABIN652493
 
BCL2L11 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN453531
 
BCL2L11 适用: 人, 小鼠 WB, ELISA, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN687277
 
BCL2L11 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7138680
 
BCL2L11 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB00963 unconjugated
Pubmed 2 references
产品编号 ABIN388101
 
BCL2L11 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030147
 
BCL2L11 适用: 人, 小鼠, 大鼠, Cow, 绵羊 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7300420
 
BCL2L11 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2F10 unconjugated
产品编号 ABIN564318
 
BCL2L11 适用: 人, 小鼠 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1C2C8 unconjugated
产品编号 ABIN298154
 
BCL2L11 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3183518
 
Verified BCL2L11 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN185253
 
BCL2L11 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1533217
 
BCL2L11 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1031197
 
BCL2L11 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7297710
 
BCL2L11 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN197552
 
BCL2L11 适用: 人, 小鼠, 大鼠 IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN197056
 
BCL2L11 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499469
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • Immunohistochemistry (IHC)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunofluorescence (IF)
    • Flow Cytometry (FACS)
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunoprecipitation (IP)
    • Immunocytochemistry (ICC)
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Enzyme Immunoassay (EIA)
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Immunochromatography (IC)
    • Immunofluorescence (fixed cells) (IF/ICC)
    • Cellular Assay (CA)
    • Dot Blot (DB)
    • Immunoassay (IA)
    • Immunostaining (ISt)
  • 适用
    • Human
    • Mouse
    • Rat
    • Monkey
    • Cow
    • Dog
    • Rabbit
    • Sheep
    • Horse
    • Pig
  • 论文引用
  • 图像
  • Preservative free only
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
    • Rat
    • Goat
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • 1C2C8
    • 1C2H4
    • 10B12
    • 13G18
    • 13G19
    • 13L1
    • 14A8
    • 2F10
    • 42C9
    • 8A7
    • CBE-2
    • PT0603R
    • R08-5A2
    • RB00963
    • RB22105
  • 抗原表位
    • pSer69
    • pSer87
    • AA 130-165
    • AA 134-160
    • pThr116
    • pThr56
    • AA 2-198
    • N-Term
    • AA 1-198
    • pSer59
    • pSer65
    • AA 2-120
    • AA 67-71
    • BH3 Domain
    • C-Term
    • AA 1-100
    • AA 1-50
    • AA 1-80
    • AA 18-186
    • AA 20-40
    • AA 22-40
    • AA 30-130
    • AA 31-80
    • AA 51-150
    • AA 80-130
    • Ala2
    • Intermediate Domain 2
    • Middle Region
    • Middle Region 2
    • Ser65
    • Ser69
    • pSer77
    • phosphorylated
  • 标记
    • 非结合性
    • Biotin
    • FITC
    • HRP
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • PE
    • APC
    • AbBy Fluor® 350
    • AbBy Fluor® 488
    • AbBy Fluor® 555
    • AbBy Fluor® 594
    • AbBy Fluor® 647
    • AbBy Fluor® 680
    • AbBy Fluor® 750
    • Cy3
    • Cy5
    • Cy5.5
    • Cy7
  • 抗体亚型
    • IgG
    • IgG1
    • Ig Fraction
    • IgG2a
    • IgG2a kappa
    • IgG2b
    • kappa
  • 蛋白类型
    • Recombinant Antibody
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • Verified
  • Supplier
    • antibodies-online
    • Signalway
    • USBio
    • Acris
    • Abbexa
    • Boster Bio
    • Abcepta
    • Assay Biotechnology Company, Inc.
    • Biomatik
    • Cohesion Biosciences
    • ProSci
    • Covalab
    • Kamiya Biomedicals
    • NSJ Bioreagents
    • RayBiotech

Latest Publications for our BIM 抗体

Peperzak, Slinger, Ter Burg, Eldering: "Functional disparities among BCL-2 members in tonsillar and leukemic B-cell subsets assessed by BH3-mimetic profiling." in: Cell death and differentiation, Vol. 24, Issue 1, pp. 111-119, (2018) (PubMed).

Jiao, Li, Zhang, Liu, Chi: "Role of Sirtuin3 in high glucose-induced apoptosis in renal tubular epithelial cells." in: Biochemical and biophysical research communications, Vol. 480, Issue 3, pp. 387-393, (2017) (PubMed).

Luan, Jin, Jiang, Tay, Lai, Liu, Liu, Guo, Li, Yan, Tseng, Zhang: "RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy." in: Autophagy, Vol. 11, Issue 7, pp. 975-94, (2015) (PubMed).

Wang, Lv, Cheng, Du, Chen, Li, Zhang: "Apoptosis induced by Ginkgo biloba (EGb761) in melanoma cells is Mcl-1-dependent." in: PLoS ONE, Vol. 10, Issue 4, pp. e0124812, (2015) (PubMed).

Lee, Maeng, Kang, Choi, Oh, Ju, Yune: "Valproic acid protects motor neuron death by inhibiting oxidative stress and endoplasmic reticulum stress-mediated cytochrome C release after spinal cord injury." in: Journal of neurotrauma, Vol. 31, Issue 6, pp. 582-94, (2014) (PubMed).

Gogada, Yadav, Liu, Tang, Zhang, Schneider, Seshadri, Sun, Aldaz, Tang, Chandra: "Bim, a proapoptotic protein, up-regulated via transcription factor E2F1-dependent mechanism, functions as a prosurvival molecule in cancer." in: The Journal of biological chemistry, Vol. 288, Issue 1, pp. 368-81, (2013) (PubMed).

Wroblewski, Jiang, Croft, Farrelly, Zhang, Hersey: "OBATOCLAX and ABT-737 induce ER stress responses in human melanoma cells that limit induction of apoptosis." in: PLoS ONE, Vol. 8, Issue 12, pp. e84073, (2013) (PubMed).

Cash, Gruber, Hartman, Henske, Simon: "Loss of the Birt-Hogg-Dubé tumor suppressor results in apoptotic resistance due to aberrant TGFβ-mediated transcription." in: Oncogene, Vol. 30, Issue 22, pp. 2534-46, (2011) (PubMed).

Loh, Liou, Jiau, Cheng, Shih, Chen: "Hepatic effects among workers exposed to ethylene glycol monoethyl ether acetate." in: Industrial health, Vol. 46, Issue 5, pp. 463-9, (2008) (PubMed).

Del Gaizo Moore, Schlis, Sallan, Armstrong, Letai: "BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia." in: Blood, Vol. 111, Issue 4, pp. 2300-9, (2008) (PubMed).

Aliases for BIM 抗体

BCL2-like 11 (bcl2l11) 抗体
BCL2 like 11 (BCL2L11) 抗体
BCL2-like 11 (apoptosis facilitator) (Bcl2l11) 抗体
BCL2 like 11 (Bcl2l11) 抗体
1500006F24Rik 抗体
BAM 抗体
bim 抗体
BIM 抗体
Bim 抗体
BIMEL 抗体
BimL 抗体
BOD 抗体
Bod 抗体
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