BIK 抗体
(BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))
The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. [provided by RefSeq, Sep 2011].
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50 results
BIK
适用: 人
ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our BIK 抗体
: "β-arrestin-2 enhances intestinal epithelial apoptosis in necrotizing enterocolitis." in: Aging, Vol. 11, Issue 19, pp. 8294-8312, (2019) (PubMed).: "Methotrexate upregulates circadian transcriptional factors PAR bZIP to induce apoptosis on rheumatoid arthritis synovial fibroblasts." in: Arthritis research & therapy, Vol. 20, Issue 1, pp. 55, (2018) (PubMed).
: "Targeting SQSTM1/p62 induces cargo loading failure and converts autophagy to apoptosis via NBK/Bik." in: Molecular and cellular biology, Vol. 34, Issue 18, pp. 3435-49, (2014) (PubMed).
: "Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity." in: Blood, Vol. 109, Issue 10, pp. 4360-7, (2007) (PubMed).
: "TNF pretreatment interferes with mitochondrial apoptosis in the mouse liver by A20-mediated down-regulation of Bax." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 10, pp. 7042-9, (2007) (PubMed).
: "The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through ..." in: The Journal of biological chemistry, Vol. 281, Issue 35, pp. 25850-66, (2006) (PubMed).
: "Transcriptional activation of the proapoptotic bik gene by E2F proteins in cancer cells." in: FEBS letters, Vol. 580, Issue 25, pp. 5905-9, (2006) (PubMed).
: "Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis." in: The EMBO journal, Vol. 24, Issue 8, pp. 1546-56, (2005) (PubMed).
: "BH3-only BIK regulates BAX,BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death." in: The Journal of biological chemistry, Vol. 280, Issue 25, pp. 23829-36, (2005) (PubMed).
: "BH-3-only BIK functions at the endoplasmic reticulum to stimulate cytochrome c release from mitochondria." in: The Journal of biological chemistry, Vol. 277, Issue 20, pp. 18053-60, (2002) (PubMed).
Aliases for BIK 抗体
BCL2 interacting killer (BIK) 抗体BCL2-interacting killer (Bik) 抗体
BCL2-interacting killer (apoptosis-inducing) (bik) 抗体
BIK 抗体
Biklk 抗体
BIP1 抗体
Blk 抗体
BP4 抗体
Nbk 抗体
NBK 抗体
si:dkey-31f5.6 抗体
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