BCL11A 抗体
(B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))
This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
recommended
BCL11A 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 3D9 unconjugated
recommended
BCL11A 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 斑马鱼, 小鸡, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
recommended
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Popular BCL11A 抗体
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Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
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Application
WB, ELISA, IHC (p), IF
Validations
- (5)
Cat. No.
ABIN526947
Quantity
100 μg
Datasheet
Datasheet
Application
WB, IHC, IHC (p)
Validations
- (4)
Cat. No.
ABIN6741578
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
IHC, ELISA
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Cat. No.
ABIN7145171
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IP
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Cat. No.
ABIN526945
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, ELISA, IHC (p)
Validations
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Cat. No.
ABIN790476
Quantity
50 μg
Datasheet
Datasheet
Reactivity
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Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN7265806
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Horse, Human, Mouse, Pig, Rat, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
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Cat. No.
ABIN2781048
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IP, ICC
Validations
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Cat. No.
ABIN7441184
Quantity
100 μL
Datasheet
Datasheet
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Application
WB, ELISA
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Cat. No.
ABIN565690
Quantity
50 μL
Datasheet
Datasheet
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Cat. No.
ABIN1989540
Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, IHC, ICC, IF
Validations
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Cat. No.
ABIN6971429
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Guinea Pig, Human, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN6746172
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Chicken, Cow, Dog, Human, Mouse, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB
Validations
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Cat. No.
ABIN927793
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN3028488
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC (p), EIA
Validations
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Cat. No.
ABIN782364
Quantity
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Datasheet
Datasheet
Latest Publications for our BCL11A 抗体
: "A natural regulatory mutation in the proximal promoter elevates fetal globin expression by creating a de novo GATA1 site." in: Blood, Vol. 133, Issue 8, pp. 852-856, (2019) (PubMed).: "Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding." in: Nature genetics, Vol. 50, Issue 4, pp. 498-503, (2018) (PubMed).
: "Bcl11a controls Flt3 expression in early hematopoietic progenitors and is required for pDC development in vivo." in: PLoS ONE, Vol. 8, Issue 5, pp. e64800, (2013) (PubMed).
: "Transcriptional silencing of {gamma}-globin by BCL11A involves long-range interactions and cooperation with SOX6." in: Genes & development, Vol. 24, Issue 8, pp. 783-98, (2010) (PubMed).
: "BCL11A represses HBG transcription in K562 cells." in: Blood cells, molecules & diseases, Vol. 42, Issue 2, pp. 144-9, (2009) (PubMed).
: "Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 5, pp. 1620-5, (2008) (PubMed).
: "Novel markers of normal and neoplastic human plasmacytoid dendritic cells." in: Blood, Vol. 111, Issue 7, pp. 3778-92, (2008) (PubMed).
: "Functional studies of BCL11A: characterization of the conserved BCL11A-XL splice variant and its interaction with BCL6 in nuclear paraspeckles of germinal center B cells." in: Molecular cancer, Vol. 5, pp. 18, (2006) (PubMed).
: "The BCL11AXL transcription factor: its distribution in normal and malignant tissues and use as a marker for plasmacytoid dendritic cells." in: Leukemia, Vol. 20, Issue 8, pp. 1439-41, (2006) (PubMed).
: "Hydroxyurea differentially modulates activator and repressors of γ-globin gene in erythroblasts of responsive and non-responsive patients with sickle cell disease in correlation with Index of ..." in: Haematologica, Vol. 102, Issue 12, pp. 1995-2004 (PubMed).
Aliases for BCL11A 抗体
B cell CLL/lymphoma 11A (zinc finger protein) (Bcl11a) 抗体B-cell CLL/lymphoma 11A (BCL11A) 抗体
B-cell CLL/lymphoma 11A L homeolog (bcl11a.L) 抗体
B-cell CLL/lymphoma 11A (Bcl11a) 抗体
B-cell CLL/lymphoma 11Aa (bcl11aa) 抗体
2810047E18Rik 抗体
BCL-11A 抗体
bcl11a 抗体
BCL11A-L 抗体
BCL11a-M 抗体
BCL11A-S 抗体
BCL11A-XL 抗体
Ctip1 抗体
CTIP1 抗体
D930021L15Rik 抗体
Evi9 抗体
EVI9 抗体
Evi9a 抗体
Evi9b 抗体
Evi9c 抗体
HBFQTL5 抗体
mKIAA1809 抗体
wu:fi09f10 抗体
zgc:136898 抗体
ZNF856 抗体
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