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BACE1 蛋白

(Beta-secretase 1 (BACE1))
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011].

Active filters:

  • 抗原: BACE1
  • Protein
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN1474867
BACE1 Protein (AA 22-457) (His tag) BACE1 · Protein 大鼠 酵母菌
  • ELISA (ELISA: 所列应用)
  • 1 mg
发货至: 中国
ABIN7943537
BACE1 Protein (His tag) BACE1 · Protein 人 大肠杆菌(E. Coli)
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
  • Imm (Immunogen: 所列应用)
  • ELISA (ELISA: 所列应用)
  • 100 μg
  • 1 mg
  • 50 μg
发货至: 中国
Protein
  • ELISA (ELISA: 所列应用)
宿主
大鼠
宿主
酵母菌
蛋白类型
Recombinant
纯度
> 90 %
产品编号 ABIN1474867
Protein
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
  • Imm (Immunogen: 所列应用)
  • ELISA (ELISA: 所列应用)
宿主
人
宿主
大肠杆菌(E. Coli)
蛋白类型
Recombinant
产品编号 ABIN7943537
100 μg (More quantities available)
发货至: 中国
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Latest Publications for our BACE1 蛋白

Mycroft-West, Devlin, Cooper, Procter, Miller, Fernig, Guerrini, Guimond, Lima, Yates, Skidmore: "Inhibition of BACE1, the β-secretase implicated in Alzheimer's disease, by a chondroitin sulfate extract from Sardina pilchardus." in: Neural regeneration research, Vol. 15, Issue 8, pp. 1546-1553, (2020) (PubMed).

Peters-Libeu, Campagna, Mitsumori, Poksay, Spilman, Sabogal, Bredesen, John: "sAβPPα is a Potent Endogenous Inhibitor of BACE1." in: Journal of Alzheimer's disease : JAD, Vol. 47, Issue 3, pp. 545-55, (2015) (PubMed).

Aliases for BACE1 蛋白

beta-secretase 1 (BACE1) 蛋白
beta-site APP cleaving enzyme 1 (Bace1) 蛋白
beta-secretase 1 (Bace1) 蛋白
beta-site APP-cleaving enzyme 1 (bace1) 蛋白
ASP2 蛋白
BACE 蛋白
Bace 蛋白
BACE1 蛋白
C76936 蛋白
HSPC104 蛋白
MGC145931 蛋白
zgc:77409 蛋白
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