BACE1 蛋白
(Beta-secretase 1 (BACE1))
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011].
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22 results
BACE1
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
1 image
BACE1
宿主: 人
宿主: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
1 image
BACE1
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
> 97 % as determined by SDS-PAGE
Active
1 image
BACE1
宿主: 人
宿主: HEK-293 Cells
Recombinant
>98 % as determined by SDS-PAGE.
1 image
2 references
BACE1
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 % as determined by reducing SDS-PAGE.
BACE1
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
WB, SDS, Imm, PC
BACE1
宿主: 人
宿主: Mammalian Cells
Recombinant
>90 % as determined by SDS-PAGE.
WB, SDS, Imm, ELISA, AcA
Active
BACE1
宿主: 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
WB, SDS, Imm, PC
BACE1
宿主: 大鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
WB, SDS, Imm, PC
BACE1
宿主: 人
宿主: Baculovirus infected Insect Cells
Recombinant
> 90 %
SDS, EAA
Active
BACE1
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Active
BACE1
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 90 % as determined by reducing SDS-PAGE.
Active
BACE1
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Latest Publications for our BACE1 蛋白
: "Inhibition of BACE1, the β-secretase implicated in Alzheimer's disease, by a chondroitin sulfate extract from Sardina pilchardus." in: Neural regeneration research, Vol. 15, Issue 8, pp. 1546-1553, (2020) (PubMed).: "sAβPPα is a Potent Endogenous Inhibitor of BACE1." in: Journal of Alzheimer's disease : JAD, Vol. 47, Issue 3, pp. 545-55, (2015) (PubMed).
Aliases for BACE1 蛋白
beta-secretase 1 (BACE1) 蛋白beta-site APP cleaving enzyme 1 (Bace1) 蛋白
beta-secretase 1 (Bace1) 蛋白
beta-site APP-cleaving enzyme 1 (bace1) 蛋白
ASP2 蛋白
BACE 蛋白
Bace 蛋白
BACE1 蛋白
C76936 蛋白
HSPC104 蛋白
MGC145931 蛋白
zgc:77409 蛋白
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