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AVPR2 蛋白

(Arginine Vasopressin Receptor 2 (AVPR2))
This gene encodes the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes the V2 receptor, the V1a and V1b vasopressin receptors, the oxytocin receptor, and isotocin and mesotocin receptors in non-mammals, is well conserved, though several members signal via other G proteins. All bind similar cyclic nonapeptide hormones. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts, where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. When the function of this gene is lost, the disease Nephrogenic Diabetes Insipidus (NDI) results. The V2 receptor is also expressed outside the kidney although its tissue localization is uncertain. When these 'extrarenal receptors' are stimulated by infusion of a V2 selective agonist (dDAVP), a variety of clotting factors are released into the bloodstream. The physiologic importance of this property is not known - its absence does not appear to be detrimental in NDI patients. The gene expression has also been described in fetal lung tissue and lung cancer associated with alternative splicing. [provided by RefSeq, Jul 2008].

6 results :

custom-made AVPR2 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7545055
 
AVPR2 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 97 % SDS, WB, Imm, PC
产品编号 ABIN7413085
 
AVPR2 宿主: 人 宿主: HEK-293 Cells Synthetic Nanodisc Imm, ELISA, cryo-EM, PhD, SPR
产品编号 ABIN7596967
 
AVPR2 宿主: 人 宿主: Mammalian Cells Synthetic Nanodisc
产品编号 ABIN7538139
 
custom-made AVPR2 宿主: 人 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA
产品编号 ABIN3097306
 
AVPR2 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant SDS, WB
产品编号 ABIN6377843
 
  • 类型 Protein
    • Protein
  • 应用范围
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • ELISA
    • Immunogen (Imm)
    • Phage Display (PhD)
    • Positive Control (PC)
    • Surface Plasmon Resonance (SPR)
    • Cryogenic electron microscopy (cryo-EM)
  • 适用
    • Human
    • Mouse
  • 图像
  • Carrier free only
  • 抗体来源
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Mammalian Cells
  • 抗原表位
    • AA 1-371
  • 标记
    • His tag
    • 非结合性
    • DYKDDDDK Tag,Strep Tag
    • Strep Tag
  • 蛋白类型
    • Recombinant
    • Synthetic Nanodisc
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • custom-made
  • Supplier
    • antibodies-online
    • Abbexa

Aliases for AVPR2 蛋白

arginine vasopressin receptor 2 (AVPR2) 蛋白
arginine vasopressin receptor 2 (Avpr2) 蛋白
ADHR 蛋白
AVPR2 蛋白
DI1 蛋白
DIR 蛋白
DIR3 蛋白
ND1 蛋白
NDI 蛋白
V2R 蛋白
VPV2R 蛋白
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