Axin 蛋白
(Axin 1 (AXIN1))
This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2010].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| Axin Protein (AA 540-768) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| Axin Protein (GST tag) | 人 | Baculovirus infected Insect Cells |
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| Axin Protein (AA 210-410) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| Axin Protein (AA 1-862) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| Axin Protein (AA 1-863) (Strep Tag) | 小鼠 | Cell-free protein synthesis (CFPS) |
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| Axin Protein (AA 654-863) (His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| Axin Protein (AA 653-862) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| Axin Protein (AA 618-827) (His tag) | 大鼠 | 大肠杆菌（E. Coli） |
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| Axin Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| Axin Protein (His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| Axin Protein (AA 653-862) (His tag) | 人 | Bacteria |
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| Axin Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 80 %
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 97 %
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 大鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 97 %
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
1 reference - 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- SDS (SDS-PAGE: 有验证图片)
- WB (Western Blotting: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Latest Publications for our Axin 蛋白
: "Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation." in: Nature chemical biology, Vol. 12, Issue 8, pp. 593-600, (2016) (PubMed).
Aliases for Axin 蛋白
axin 1 (AXIN1) 蛋白axin 1 S homeolog (axin1.S) 蛋白
axin 1 L homeolog (axin1.L) 蛋白
axin 1 (Axin1) 蛋白
axin 1 (axin1) 蛋白
AI316800 蛋白
axin 蛋白
AXIN 蛋白
Axin 蛋白
AXIN1 蛋白
AXIN1-RGS 蛋白
Fu 蛋白
fused 蛋白
Kb 蛋白
Ki 蛋白
kinky 蛋白
knobbly 蛋白
LOC100226467 蛋白
PPP1R49 蛋白
wu:fi22e03 蛋白
wu:fj14c08 蛋白
wu:fk11b03 蛋白
xAxin 蛋白
zgc:109872 蛋白
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