APPL1 抗体
(Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 1 (APPL1))
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008].
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Latest Publications for our APPL1 抗体
: "Fiber type-specific differences in glucose uptake by single fibers from skeletal muscles of 9- and 25-month-old rats." in: The journals of gerontology. Series A, Biological sciences and medical sciences, Vol. 67, Issue 12, pp. 1286-94, (2012) (PubMed).: "A novel method to measure glucose uptake and myosin heavy chain isoform expression of single fibers from rat skeletal muscle." in: Diabetes, Vol. 61, Issue 5, pp. 995-1003, (2012) (PubMed).
: "Effects of polysaccharides from Morchella conica on nitric oxide production in lipopolysaccharide-treated macrophages." in: Applied microbiology and biotechnology, Vol. 94, Issue 3, pp. 763-71, (2012) (PubMed).
: "Mechanisms for increased insulin-stimulated Akt phosphorylation and glucose uptake in fast- and slow-twitch skeletal muscles of calorie-restricted rats." in: American journal of physiology. Endocrinology and metabolism, Vol. 300, Issue 6, pp. E966-78, (2011) (PubMed).
: "Insulin resistance for glucose uptake and Akt2 phosphorylation in the soleus, but not epitrochlearis, muscles of old vs. adult rats." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 108, Issue 6, pp. 1631-40, (2010) (PubMed).
: "APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function." in: Nature cell biology, Vol. 8, Issue 5, pp. 516-23, (2006) (PubMed).
: "Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2." in: Oncogene, Vol. 18, Issue 35, pp. 4891-8, (1999) (PubMed).
Aliases for APPL1 抗体
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 (APPL1) 抗体adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 (Appl1) 抗体
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 (Appl1) 抗体
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