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APP 蛋白

(Amyloid beta (A4) Precursor Protein (APP))
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Amyloid beta (A4) Precursor Protein (APP) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) Amyloid beta (A4) Precursor Protein (APP) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) Amyloid beta (A4) Precursor Protein (APP) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) (ABIN2714676)

APP 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

Amyloid beta (A4) Precursor Protein (APP) (AA 18-286) protein (rho-1D4 tag) Amyloid beta (A4) Precursor Protein (APP) (AA 18-286) protein (rho-1D4 tag) Amyloid beta (A4) Precursor Protein (APP) (AA 18-286) protein (rho-1D4 tag) (ABIN3132889)

Crystallography grade APP 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

Amyloid beta (A4) Precursor Protein (APP) (AA 672-713) protein (rho-1D4 tag) Amyloid beta (A4) Precursor Protein (APP) (AA 672-713) protein (rho-1D4 tag) Amyloid beta (A4) Precursor Protein (APP) (AA 672-713) protein (rho-1D4 tag) (ABIN3132894)

Crystallography grade APP 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

APP 蛋白 by Grade

Find APP 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

APP 蛋白 by Origin

Find APP 蛋白 for a variety of species such as anti-Human APP, anti-Mouse APP, anti-Rat APP. The species listed below are among those available. Click on a link to go to the corresponding products.

APP 蛋白 by Source

Find APP 蛋白 with a specific Source. The Source listed below are among those available. Click on a link to go to the corresponding products.

APP 蛋白 by 蛋白类型

Find APP 蛋白 with a specific 蛋白类型. The 蛋白类型 listed below are among those available. Click on a link to go to the corresponding products.

APP 蛋白 by 应用范围

Find APP 蛋白 validated for a specific application such as WB, SDS, ELISA, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular APP 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3132895
Quantity 0.25 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3132898
Quantity 0.25 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3132896
Quantity 0.25 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3132897
Quantity 0.25 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3132899
Quantity 0.25 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3132900
Quantity 0.25 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3088391
Quantity 0.5 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3088393
Quantity 0.5 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3088392
Quantity 0.5 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3088394
Quantity 0.5 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3088395
Quantity 0.5 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3088397
Quantity 0.5 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3088396
Quantity 0.5 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3088398
Quantity 0.5 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3132890
Quantity 0.25 mg
Datasheet Datasheet

Latest Publications for our APP 蛋白

Planque, Nishiyama, Sonoda, Lin, Taguchi, Hara, Kolodziej, Mitsuda, Gonzalez, Sait, Fukuchi, Massey, Friedland, ONuallain, Sigurdsson, Paul: "Specific amyloid β clearance by a catalytic antibody construct." in: The Journal of biological chemistry, Vol. 290, Issue 16, pp. 10229-41, (2015) (PubMed).

Yoshikai, Sasaki, Doh-ura, Furuya, Sakaki: "Genomic organization of the human amyloid beta-protein precursor gene." in: Gene, Vol. 87, Issue 2, pp. 257-63, (1990) (PubMed).

Lemaire, Salbaum, Multhaup, Kang, Bayney, Unterbeck, Beyreuther, Müller-Hill: "The PreA4(695) precursor protein of Alzheimer's disease A4 amyloid is encoded by 16 exons." in: Nucleic acids research, Vol. 17, Issue 2, pp. 517-22, (1989) (PubMed).

Ponte, Gonzalez-DeWhitt, Schilling, Miller, Hsu, Greenberg, Davis, Wallace, Lieberburg, Fuller: "A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors." in: Nature, Vol. 331, Issue 6156, pp. 525-7, (1988) (PubMed).

Kang, Lemaire, Unterbeck, Salbaum, Masters, Grzeschik, Multhaup, Beyreuther, Müller-Hill: "The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor." in: Nature, Vol. 325, Issue 6106, pp. 733-6, (1987) (PubMed).

Aliases for APP 蛋白

amyloid beta precursor protein (APP) 蛋白
zinc finger protein 42 (Zfp42) 蛋白
amyloid beta (A4) precursor protein (APP) 蛋白
amyloid beta precursor protein (app) 蛋白
beta amyloid protein precursor-like (Appl) 蛋白
amyloid beta precursor protein (App) 蛋白
amyloid beta (A4) precursor protein (App) 蛋白
amyloid beta (A4) precursor protein a (appa) 蛋白
amyloid beta precursor protein L homeolog (app.L) 蛋白
AAA 蛋白
aaa 蛋白
ABETA 蛋白
abeta 蛋白
Abeta 蛋白
ABPP 蛋白
abpp 蛋白
Abpp 蛋白
AD1 蛋白
ad1 蛋白
Adap 蛋白
Ag 蛋白
APP 蛋白
app 蛋白
APP-like 蛋白
APPI 蛋白
appi 蛋白
APPL 蛋白
appl 蛋白
BcDNA:GH04413 蛋白
betaApp 蛋白
CG7727 蛋白
CTFgamma 蛋白
ctfgamma 蛋白
CVAP 蛋白
cvap 蛋白
Cvap 蛋白
Dmel\\CG7727 蛋白
E030013M08Rik 蛋白
EG:65F1.5 蛋白
PN-II 蛋白
PN2 蛋白
pn2 蛋白
Rex-1 蛋白
Rex1 蛋白
wu:fj34d10 蛋白
wu:fk65e12 蛋白
Zfp-42 蛋白
zgc:85740 蛋白
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