This gene is a member of the apolipoprotein family. Members of this protein family are involved in the transport and metabolism of lipids. The encoded protein associates with HDL, LDL and VLDL lipoproteins and is characterized by chondroitin-sulfate glycosylation. This protein may be involved in preventing lipid accumulation in the myocardium in obese and diabetic patients. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 4, 5, 12 and 16.[provided by RefSeq, Sep 2009].
Guarani, Jardel, Chrétien, Lombès, Bénit, Labasse, Lacène, Bourillon, Imbard, Benoist, Dorboz, Gilleron, Goetzman, Gaignard, Slama, Elmaleh-Bergès, Romero, Rustin, Ogier de Baulny, Paulo, Harper et al.: "QIL1 mutation causes MICOS disassembly and early onset fatal mitochondrial encephalopathy with liver disease. ..." in: eLife, Vol. 5, (2016) (PubMed).
Guarani, McNeill, Paulo, Huttlin, Fröhlich, Gygi, Van Vactor, Harper: "QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology." in: eLife, Vol. 4, (2015) (PubMed).
Lamant, Smih, Harmancey, Philip-Couderc, Pathak, Roncalli, Galinier, Collet, Massabuau, Senard, Rouet: "ApoO, a novel apolipoprotein, is an original glycoprotein up-regulated by diabetes in human heart." in: The Journal of biological chemistry, Vol. 281, Issue 47, pp. 36289-302, (2006) (PubMed).
Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, (2003) (PubMed).
Aliases for Apolipoprotein O 抗体
apolipoprotein O, a (apooa) 抗体 apolipoprotein O (apoo) 抗体 apolipoprotein O (APOO) 抗体 apolipoprotein O (Apoo) 抗体 apolipoprotein O L homeolog (apoo.L) 抗体 apolipoprotein O, b (apoob) 抗体 0610008C08Rik 抗体 1110019O03Rik 抗体 fam121b 抗体 FAM121B 抗体 fp74f12 抗体 MGC79016 抗体 my025 抗体 RGD1565289 抗体 si:rp71-1f1.3 抗体 wu:fp74f12 抗体 wu:fr42a11 抗体 zgc:103766 抗体 zgc:123314 抗体