(Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide 1 (APOBEC1))
This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs. [provided by RefSeq, Jul 2008].
Chester, Somasekaram, Tzimina, Jarmuz, Gisbourne, OKeefe, Scott, Navaratnam: "The apolipoprotein B mRNA editing complex performs a multifunctional cycle and suppresses nonsense-mediated decay." in: The EMBO journal, Vol. 22, Issue 15, pp. 3971-82, (2003) (PubMed).
Blanc, Kennedy, Davidson: "A novel nuclear localization signal in the auxiliary domain of apobec-1 complementation factor regulates nucleocytoplasmic import and shuttling." in: The Journal of biological chemistry, Vol. 278, Issue 42, pp. 41198-204, (2003) (PubMed).
Wedekind, Dance, Sowden, Smith: "Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business." in: Trends in genetics : TIG, Vol. 19, Issue 4, pp. 207-16, (2003) (PubMed).
Lau, Chan: "Involvement of a chaperone regulator, Bcl2-associated athanogene-4, in apolipoprotein B mRNA editing." in: The Journal of biological chemistry, Vol. 278, Issue 52, pp. 52988-96, (2003) (PubMed).