GSK3 alpha 抗体 (pSer21)
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- 抗原 See all GSK3 alpha (GSK3a) 抗体
- GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))
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抗原表位
- pSer21
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GSK3 alpha antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Fluorescence Microscopy (FM)
- Supplier Product No.
- 600-401-429
- Supplier
- Rockland
- 原理
- GSK3 Alpha phospho S21 Antibody
- 交叉反应 （详细）
- This affinity-purified antibody is directed against the phosphorylated form of human GSK3A at the pS 21 residue.
- 产品特性
- Synonyms: rabbit anti-GSK3 alpha pS21 antibody, rabbit anti-GSK3α pS21 antibody, GSK 3 alpha pS21 antibody, Glycogen synthase kinase-3 alpha antibody, phosphorylated GSK-3 alpha antibody, GSK 3A antibody, GSK-3A antibody, GSK3alpha antibody, Serine/threonine-protein kinase GSK3A
- 纯化方法
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
- 过滤
- Sterile filtered
- 免疫原
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Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the N-Terminal region near aa 1-25 of human GSK3 alpha.
Immunogen Type: Conjugated Peptide
- 亚型
- IgG
- Top Product
- Discover our top product GSK3a Primary Antibody
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anti-Glycogen Synthase Kinase 3 alpha (GSK3a) (pSer21) antibody
GSK3a 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 alpha (GSK3a) (pSer21) antibodyGSK3a 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 alpha (GSK3a) antibodyKO Validated GSK3a 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-Glycogen Synthase Kinase 3 alpha (GSK3a) (AA 122-406) antibodyGSK3a 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 alpha (GSK3a) (AA 76-105), (N-Term) antibodyGSK3a 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3817-3818 unconjugated
anti-Glycogen Synthase Kinase 3 alpha (GSK3a) (AA 409-483) antibodyGSK3a 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 alpha (GSK3a) antibodyGSK3a 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 9D5G1 unconjugated
anti-Glycogen Synthase Kinase 3 alpha (GSK3a) antibodyGSK3a 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 6G2F1 unconjugated
anti-Glycogen Synthase Kinase 3 alpha (GSK3a) (Ser21) antibodyGSK3a 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 alpha (GSK3a) (AA 36-118) antibodyGSK3a 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Application Note: This affinity-purified antibody has been tested for use in ELISA and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 52 kDa in size corresponding to GSK3A by western blotting in the appropriate cell lysate or extract. Less than 1 % reactivity is observed against the non-phosphorylated form of the immunizing peptide. This antibody is phospho specific for pS21 of GSK3A.
Western Blot Dilution: 1:500 - 1:3,000
ELISA Dilution: 1:2,000 - 1:10,000
IF Microscopy Dilution: User Optimized
Other: User Optimized
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.28 mg/mL
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 12 months
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- 抗原
- GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))
- 别名
- GSK3A (GSK3a 产品)
- 背景
- Background: Glycogen synthase kinase 3 alpha (GSK3A) belongs to the ser/thr family of protein kinases, Cdc2/cdkx subfamily, gsk-3 subsubfamily. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, myb, and the transcription factor c-jun. GSK3A is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. Two isoforms, alpha (GSK3A) and beta (GSK3B), show a high degree of amino acid homology. GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.
- 基因ID
- 2931, 49574532
- UniProt
- P49840
- 途径
- PI3K-Akt Signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, BCR Signaling, Warburg Effect
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