MELK 抗体 (AA 637-651)
Quick Overview for MELK 抗体 (AA 637-651) (ABIN969538)
抗原
See all MELK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 637-651
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原理
- MELK Antibody
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序列
- VYKRLVEDIL SSCKV
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纯化方法
- Purified antibody
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免疫原
- Synthesized peptide of human MELK(AA: 637-651:C-VYKRLVEDILSSCKV).
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亚型
- IgG2a
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway." in: Neuro-oncology, Vol. 13, Issue 6, pp. 622-34, (2011) (PubMed).
: "Dysregulated expression of Fau and MELK is associated with poor prognosis in breast cancer." in: Breast cancer research : BCR, Vol. 11, Issue 4, pp. R60, (2009) (PubMed).
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Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway." in: Neuro-oncology, Vol. 13, Issue 6, pp. 622-34, (2011) (PubMed).
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- MELK (Maternal Embryonic Leucine Zipper Kinase (MELK))
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别名
- MELK
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背景
- Maternal embryonic leucine-zipper kinase (MELK) is a key regulator of survival of stemlike GBM cells in vitro. MELK expression is increased in breast cancer tissue and this increase is also associated with poor patient survival, as predicted for a candidate oncogene.
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分子量
- 74.6 kDa
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基因ID
- 9833
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UniProt
- Q14680
抗原
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