INCENP 抗体 (AA 369-583)
(2 references)Quick Overview for INCENP 抗体 (AA 369-583) (ABIN969529)
抗原
See all INCENP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 369-583
-
原理
- INCENP Antibody
-
纯化方法
- Purified antibody
-
免疫原
- Purified recombinant fragment of human INCENP (AA: 369-583) expressed in E. Coli.
-
亚型
- IgG1
-
-
anti-Inner Centromere Protein Antigens 135/155kDa (INCENP) antibody
INCENP 适用: 人 WB, IF, FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 3D2 unconjugated
anti-Inner Centromere Protein Antigens 135/155kDa (INCENP) (AA 369-583) antibodyINCENP 适用: 人 WB, FACS, ELISA, IHC, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Inner Centromere Protein Antigens 135/155kDa (INCENP) antibodyINCENP 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Inner Centromere Protein Antigens 135/155kDa (INCENP) (AA 785-914) antibodyINCENP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Inner Centromere Protein Antigens 135/155kDa (INCENP) (AA 231-398) antibodyINCENP 适用: 人, 小鼠 IF, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Inner Centromere Protein Antigens 135/155kDa (INCENP) antibodyINCENP 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
-
: "Mitotic kinase Aurora-B is regulated by SUMO-2/3 conjugation/deconjugation during mitosis." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 16, Issue 6, pp. 652-69, (2011) (PubMed).
: "INCENP-aurora B interactions modulate kinase activity and chromosome passenger complex localization." in: The Journal of cell biology, Vol. 187, Issue 5, pp. 637-53, (2009) (PubMed).
-
: "Mitotic kinase Aurora-B is regulated by SUMO-2/3 conjugation/deconjugation during mitosis." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 16, Issue 6, pp. 652-69, (2011) (PubMed).
-
- INCENP (Inner Centromere Protein Antigens 135/155kDa (INCENP))
-
别名
- INCENP
-
背景
- In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger,' or transiently interacting, proteins (reviewed by Choo, 1997). The constitutive proteins include CENPA (centromere protein A, MIM 117139), CENPB (MIM 117140), CENPC1 (MIM 117141), and CENPD (MIM 117142). The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle (Earnshaw and Mackay, 1994 [PubMed 8088460]). These include CENPE (MIM 117143), MCAK (MIM 604538), KID (MIM 603213), cytoplasmic dynein (e.g., MIM 600112), CliPs (e.g., MIM 179838), and CENPF/mitosin (MIM 600236). The inner centromere proteins (INCENPs) (Earnshaw and Cooke, 1991 [PubMed 1860899]), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-metaphase. During telophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis
-
分子量
- 105.4 kDa
-
基因ID
- 3619
-
UniProt
- Q9NQS7
-
途径
- Cell Division Cycle
抗原
-
