PRTN3 抗体
(2 references)Quick Overview for PRTN3 抗体 (ABIN969498)
抗原
See all PRTN3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Proteinase 3 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human Proteinase 3 expressed in E. Coli.
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亚型
- IgG2b
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anti-Proteinase 3 (PRTN3) (AA 71-247) antibody
PRTN3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 88-98) antibodyVerified PRTN3 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 24-249) antibodyPRTN3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 1-170) antibodyPRTN3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 228-256), (C-Term) antibodyPRTN3 适用: 人 WB 宿主: 兔 Polyclonal RB40945 unconjugated
anti-Proteinase 3 (PRTN3) (AA 1-256) antibodyPRTN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 1-256) antibodyPRTN3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 139-248) antibodyPRTN3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 76-125) antibodyPRTN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Proteinase 3, the Wegener autoantigen, is externalized during neutrophil apoptosis: evidence for a functional association with phospholipid scramblase 1 and interference with macrophage phagocytosis." in: Blood, Vol. 110, Issue 12, pp. 4086-95, (2007) (PubMed).
: "Increased neutrophil membrane expression and plasma level of proteinase 3 in systemic vasculitis are not a consequence of the - 564 A/G promotor polymorphism." in: Clinical and experimental immunology, Vol. 145, Issue 1, pp. 63-70, (2006) (PubMed).
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: "Proteinase 3, the Wegener autoantigen, is externalized during neutrophil apoptosis: evidence for a functional association with phospholipid scramblase 1 and interference with macrophage phagocytosis." in: Blood, Vol. 110, Issue 12, pp. 4086-95, (2007) (PubMed).
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- PRTN3 (Proteinase 3 (PRTN3))
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别名
- Proteinase 3
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背景
- Proteinase 3, also known as PRTN3. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.
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分子量
- 28 kDa
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基因ID
- 5657
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UniProt
- P24158
抗原
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