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PRTN3 抗体 (C-Term)

PRTN3 适用: 人 WB 宿主: 兔 Polyclonal RB40945 unconjugated
产品编号 ABIN1881695
发货至: 中国
  • 抗原 See all PRTN3 抗体
    PRTN3 (Proteinase 3 (PRTN3))
    抗原表位
    • 13
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 228-256, C-Term
    适用
    • 70
    • 11
    • 6
    • 1
    • 1
    • 1
    宿主
    • 51
    • 27
    • 1
    • 1
    • 1
    克隆类型
    • 56
    • 25
    多克隆
    标记
    • 43
    • 10
    • 9
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRTN3 antibody is un-conjugated
    应用范围
    • 59
    • 34
    • 21
    • 11
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This PRTN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-256 amino acids from the C-terminal region of human PRTN3.
    克隆位点
    RB40945
    亚型
    Ig Fraction
    Top Product
    Discover our top product PRTN3 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Kuhl, Korkmaz, Utecht, Kniepert, Schönermarck, Specks, Jenne: "Mapping of conformational epitopes on human proteinase 3, the autoantigen of Wegener's granulomatosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 1, pp. 387-99, (2010) (PubMed).

    Abdgawad, Gunnarsson, Bengtsson, Geborek, Nilsson, Segelmark, Hellmark: "Elevated neutrophil membrane expression of proteinase 3 is dependent upon CD177 expression." in: Clinical and experimental immunology, Vol. 161, Issue 1, pp. 89-97, (2010) (PubMed).

    Hajjar, Broemstrup, Kantari, Witko-Sarsat, Reuter: "Structures of human proteinase 3 and neutrophil elastase--so similar yet so different." in: The FEBS journal, Vol. 277, Issue 10, pp. 2238-54, (2010) (PubMed).

    Källquist, Rosén, Nordenfelt, Calafat, Janssen, Persson, Hansson, Olsson: "Neutrophil elastase and proteinase 3 trafficking routes in myelomonocytic cells." in: Experimental cell research, Vol. 316, Issue 19, pp. 3182-96, (2010) (PubMed).

    Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

  • 抗原
    PRTN3 (Proteinase 3 (PRTN3))
    别名
    PRTN3 (PRTN3 产品)
    别名
    ela2 antibody, MGC132250 antibody, ACPA antibody, AGP7 antibody, C-ANCA antibody, CANCA antibody, MBN antibody, MBT antibody, NP-4 antibody, NP4 antibody, P29 antibody, PR-3 antibody, PR3 antibody, mPR3 antibody, proteinase 3 L homeolog antibody, proteinase 3 antibody, prtn3.L antibody, PRTN3 antibody, Prtn3 antibody
    背景
    Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.
    分子量
    27807
    NCBI登录号
    NP_002768
    UniProt
    P24158
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