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DAXX 抗体

This anti-DAXX antibody is a 小鼠 单克隆 antibody detecting DAXX in WB, ELISA, FACS 和 ICC. Suitable for 人.
产品编号 ABIN969493
发货至: 中国

Quick Overview for DAXX 抗体 (ABIN969493)

抗原

See all DAXX 抗体
DAXX (Death-Domain Associated Protein (DAXX))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This DAXX antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

7A11
  • 原理

    DAXX Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human DAXX expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    DAXX (Death-Domain Associated Protein (DAXX))

    别名

    DAXX

    背景

    DAXX (death-domain associated protein), it is a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.

    分子量

    81 kDa

    基因ID

    1616

    UniProt

    Q9UER7

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway
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