SNCG (Breast Cancer-Specific Protein 1) 抗体
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- 抗原
- SNCG (Breast Cancer-Specific Protein 1)
- 适用
- 人
- 宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- Immunohistochemistry (IHC), ELISA
- 原理
- SNCG (breast cancer-specific protein 1) Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of SNCG expressed in E. Coli.
- 克隆位点
- 1H10D2
- 亚型
- IgG1
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- 应用备注
- ELISA: 1/10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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gamma-synuclein has a dynamic intracellular localization." in: Cell motility and the cytoskeleton, Vol. 63, Issue 8, pp. 447-58, (2006) (PubMed).
: "Polylysine cross-links axoplasmic neurofilaments into tight bundles." in: Cell motility and the cytoskeleton, Vol. 31, Issue 1, pp. 9-21, (1995) (PubMed).
: "
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gamma-synuclein has a dynamic intracellular localization." in: Cell motility and the cytoskeleton, Vol. 63, Issue 8, pp. 447-58, (2006) (PubMed).
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- 抗原
- SNCG (Breast Cancer-Specific Protein 1)
- 背景
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Description: SNCG(also designated gamma-synuclein or breast cancer-specific protein 1),with 127-amino acid protein(about 14 kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.
Aliases: SR, BCSG1
- 基因ID
- 6623
- HGNC
- 6623
- UniProt
- O76070
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