TYRO3 抗体
(1 reference)Quick Overview for TYRO3 抗体 (ABIN969449)
抗原
See all TYRO3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- TYRO3 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant extracellular fragment of human TYRO3 fused with hIgGFc tag expressed in HEK293 cell line.
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亚型
- IgG1
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anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibody
TYRO3 适用: 人 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 4C8 unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibodyTYRO3 适用: 人 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 5B4 unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibodyTYRO3 适用: 人 WB, IHC, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 2C4 unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 50-150) antibodyTYRO3 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 4F6 unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 728-873) antibodyTYRO3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 1-890) antibodyTYRO3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibodyTYRO3 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 138-321) antibodyTYRO3 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 6D6F10 unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 842-873), (C-Term) antibodyTYRO3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1489 unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibodyTYRO3 适用: 小鼠 WB 宿主: 小鼠 Monoclonal 5A3 unconjugated
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Transforming activity of receptor tyrosine kinase tyro3 is mediated, at least in part, by the PI3 kinase-signaling pathway." in: Blood, Vol. 95, Issue 2, pp. 633-8, (2000) (PubMed).
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: "Transforming activity of receptor tyrosine kinase tyro3 is mediated, at least in part, by the PI3 kinase-signaling pathway." in: Blood, Vol. 95, Issue 2, pp. 633-8, (2000) (PubMed).
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- TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))
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别名
- TYRO3
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背景
- TYRO3: Tyrosine-protein kinase, also known as BYK, Brt, Dtk, Sky. Entrez Protein: NP_006284. It belongs to the Tyr protein kinase family (AXL/UFO subfamily). The UFO family of receptor tyrosine kinases is comprised of subfamily members Rse(also referred to as Tyro3 or Sky) and UFO (also called Tyro7 or Axl). Two distinct isoforms of Rse, designated Brt and Etk-2, have been described. Brt differs from Rse at its C-terminus, but more importantly lacks the N-terminal 31 amino acid signal peptide sequence present in Rse, which is replaced by a 27 amino acid Brt-specific sequence. It has been suggested that as a result of this alternative splicing event, Brt resides in the cytoplasm, unlike Rse which is expressed on the cell surface. Ekt-2 also lacks an N-terminal signal peptide which is substituted with a 45 amino acid Ekt-2-specific sequence. Protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.
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分子量
- 96.9 kDa
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UniProt
- Q06418
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途径
- RTK signaling
抗原
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