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STAT5B 抗体

STAT5B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5B3 unconjugated
产品编号 ABIN969422
发货至: 中国
  • 抗原 See all STAT5B 抗体
    STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This STAT5B antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human STAT5B expressed in E. coli.
    克隆位点
    5B3
    亚型
    IgG1
    Top Product
    Discover our top product STAT5B Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • 抗原
    STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))
    别名
    STAT5B (STAT5B 产品)
    别名
    STAT5 antibody, stat5 antibody, STAT5A antibody, STAT5B antibody, signal transducer and activator of transcription 5B antibody, signal transducer and activator of transcription 5B S homeolog antibody, Signal transducer and activator of transcription 5B antibody, STAT5B antibody, Stat5b antibody, stat5b.S antibody, LOC490969 antibody, sta5b antibody, LOC100566752 antibody, LOC100052954 antibody
    背景

    Description: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

    Aliases: STAT5, STAT5B

    分子量
    90 kDa
    基因ID
    6777
    HGNC
    6777
    途径
    JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
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