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SOD1 抗体

This anti-SOD1 antibody is a 小鼠 单克隆 antibody detecting SOD1 in WB, ELISA, ICC 和 FACS. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN969412
发货至: 中国

Quick Overview for SOD1 抗体 (ABIN969412)

抗原

See all SOD1 抗体
SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

适用

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人, 小鼠

宿主

  • 218
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小鼠

克隆类型

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  • 63
单克隆

标记

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This SOD1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

克隆位点

6F5
  • 原理

    SOD1 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human SOD1 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Kawamata, Manfredi: "Different regulation of wild-type and mutant Cu,Zn superoxide dismutase localization in mammalian mitochondria." in: Human molecular genetics, Vol. 17, Issue 21, pp. 3303-17, (2008) (PubMed).

  • 抗原

    SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

    别名

    SOD1

    背景

    SOD1 (superoxide dismutase 1, soluble), also known as ALS. The protein binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis (ALS), a progressive degenerative disease of motor neurons. Rare transcript variants have been reported for this gene.

    分子量

    18 kDa

    基因ID

    6647

    UniProt

    P00441

    途径

    Sensory Perception of Sound, Transition Metal Ion Homeostasis
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