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PTK7 抗体

This anti-PTK7 antibody is a 小鼠 单克隆 antibody detecting PTK7 in WB, IHC 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN969374
发货至: 中国

Quick Overview for PTK7 抗体 (ABIN969374)

抗原

See all PTK7 抗体
PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

适用

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宿主

  • 51
  • 9
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  • 1
  • 1
小鼠

克隆类型

  • 54
  • 10
单克隆

标记

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  • 3
This PTK7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

4F9
  • 原理

    PTK7 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human PTK7 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shin, Maeng, Jung, Min, Kwon, Lee: "Soluble PTK7 inhibits tube formation, migration, and invasion of endothelial cells and angiogenesis." in: Biochemical and biophysical research communications, Vol. 371, Issue 4, pp. 793-8, (2008) (PubMed).

  • 抗原

    PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

    别名

    PTK7

    背景

    Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene.Tissue specificity: Highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. But not expressed in colon.

    分子量

    118 kDa

    基因ID

    5754

    UniProt

    Q13308

    途径

    RTK signaling, Tube Formation
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