LIMS1 抗体
(2 references)Quick Overview for LIMS1 抗体 (ABIN969354)
抗原
See all LIMS1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PINCH Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human PINCH expressed in E. Coli.
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亚型
- IgG1
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anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) (AA 1-325) antibody
LIMS1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibodyLIMS1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibodyLIMS1 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibodyLIMS1 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) (AA 68-303) antibodyLIMS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibodyLIMS1 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Structural basis of focal adhesion localization of LIM-only adaptor PINCH by integrin-linked kinase." in: The Journal of biological chemistry, Vol. 284, Issue 9, pp. 5836-44, (2009) (PubMed).
: "The structural basis of integrin-linked kinase-PINCH interactions." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 52, pp. 20677-82, (2008) (PubMed).
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: "Structural basis of focal adhesion localization of LIM-only adaptor PINCH by integrin-linked kinase." in: The Journal of biological chemistry, Vol. 284, Issue 9, pp. 5836-44, (2009) (PubMed).
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- LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
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别名
- PINCH
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背景
- The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
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分子量
- 37 kDa
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基因ID
- 3987
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UniProt
- P48059
抗原
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