OLIG2 抗体
Quick Overview for OLIG2 抗体 (ABIN969331)
抗原
See all OLIG2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- OLIG2 Antibody
-
纯化方法
- Ascitic fluid
-
免疫原
- Purified recombinant fragment of human OLIG2 expressed in E. Coli.
-
亚型
- IgG1
-
-
-
-
应用备注
-
ELISA: 1/10000
ICC: 1/200 - 1/1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
-
Absence of OLIG2 mutations in patients presenting with a severe Pelizaeus-Merzbacher-like leukodystrophy associated with motor neuron dysfunction." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 147B, Issue 4, pp. 538-9, (2008) (PubMed).
: "Predominant expression of OLIG2 over ID2 in oligodendroglial tumors." in: Virchows Archiv : an international journal of pathology, Vol. 450, Issue 5, pp. 575-84, (2007) (PubMed).
: "
-
Absence of OLIG2 mutations in patients presenting with a severe Pelizaeus-Merzbacher-like leukodystrophy associated with motor neuron dysfunction." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 147B, Issue 4, pp. 538-9, (2008) (PubMed).
-
- OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))
-
别名
- OLIG2
-
背景
- This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14,21)(q11.2,q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.
-
分子量
- 32 kDa
-
UniProt
- Q13516
抗原
-