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OCT4 抗体

This anti-OCT4 antibody is a 小鼠 单克隆 antibody detecting OCT4 in WB, ELISA, ICC 和 FACS. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN969329
发货至: 中国

Quick Overview for OCT4 抗体 (ABIN969329)

抗原

See all OCT4 (POU5F1) 抗体
OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This OCT4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

克隆位点

7E7
  • 原理

    4-Oct Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Synthesized peptide derived from internal of human Oct4.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Wang, Dai: "Concise review: isoforms of OCT4 contribute to the confusing diversity in stem cell biology." in: Stem cells (Dayton, Ohio), Vol. 28, Issue 5, pp. 885-93, (2010) (PubMed).

    Stefanovic, Pucéat: "[The dual role of OCT4]." in: Médecine sciences : M/S, Vol. 26, Issue 4, pp. 411-6, (2010) (PubMed).

    Rose, Behm, Drgon, Johnson, Uhl: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, (2010) (PubMed).

  • 抗原

    OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

    别名

    4-Oct

    背景

    This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6,22)(p21,q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. (provided by RefSeq).Tissue specificity: Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.

    分子量

    45 kDa

    UniProt

    Q01860

    途径

    Stem Cell Maintenance
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