NME1 抗体
(3 references)Quick Overview for NME1 抗体 (ABIN969317)
抗原
See all NME1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- NME1 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human NME1 expressed in E. Coli.
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亚型
- IgG1
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anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 43-152) antibody
NME1 适用: 人 WB, ELISA, IHC (p), IF, IP 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 1-152) antibodyNME1 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 2H1 unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) antibodyNME1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4H2 unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (N-Term) antibodyNME1 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, 豚鼠 WB, IHC, DB 宿主: 兔 Polyclonal unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 6-147) antibodyNME1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (N-Term) antibodyNME1 适用: 人, 小鼠, 大鼠, 犬, 猴, Pig, Cow, 马, 兔, 小鸡, 非洲爪蟾, 斑马鱼, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (C-Term) antibodyNME1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (N-Term) antibodyNME1 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow, 小鸡, 非洲爪蟾, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 137-152), (C-Term) antibodyNME1 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) antibodyNME1 适用: 人, 大鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 2C1 unconjugated
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Transglutaminase 2 and nucleoside diphosphate kinase activity are correlated in epithelial membranes and are abnormal in cystic fibrosis." in: FEBS letters, Vol. 583, Issue 17, pp. 2789-92, (2009) (PubMed).
: "IFI16 and NM23 bind to a common DNA fragment both in the P53 and the cMYC gene promoters." in: Journal of cellular biochemistry, Vol. 106, Issue 4, pp. 666-72, (2009) (PubMed).
: "Multiple functions of Nm23-H1 are regulated by oxido-reduction system." in: PLoS ONE, Vol. 4, Issue 11, pp. e7949, (2009) (PubMed).
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: "Transglutaminase 2 and nucleoside diphosphate kinase activity are correlated in epithelial membranes and are abnormal in cystic fibrosis." in: FEBS letters, Vol. 583, Issue 17, pp. 2789-92, (2009) (PubMed).
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- NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))
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别名
- NME1
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背景
- Non-metastatic cells 1,protein,with a nm23 nucleoside diphosphate kinase gene family,involved in the phosphorylation of nucleoside diphosphates,with a reduced expression in tumor progression to the metastatic phenotype,mutated in agressive neuroblastoma,expressed in lung carcinoma cell lines not in normal lung,pyrimidine biosynthetic pathway. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. Has tumor metastasis-suppressive capacity.Tissue specificity: Isoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation. Isoform 3 is ubiquitously expressed.
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分子量
- 17 kDa
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UniProt
- P15531
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途径
- Apoptosis, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process
抗原
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