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NKX3-1 抗体

This anti-NKX3-1 antibody is a 小鼠 单克隆 antibody detecting NKX3-1 in WB, IHC, ELISA 和 FACS. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN969316
发货至: 中国

Quick Overview for NKX3-1 抗体 (ABIN969316)

抗原

See all NKX3-1 抗体
NKX3-1 (NK3 Homeobox 1 (NKX3-1))

适用

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宿主

  • 72
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  • 1
小鼠

克隆类型

  • 75
  • 51
单克隆

标记

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This NKX3-1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

克隆位点

4H4
  • 原理

    NKX3A Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human NKX3A expressed in E. Coli.

    亚型

    IgG2b
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Zhang, Liu, Zhang, Guan, Chen, Cui, Liu, Jiang: "Gene expression profiles in the PC-3 human prostate cancer cells induced by NKX3.1." in: Molecular biology reports, Vol. 37, Issue 3, pp. 1505-12, (2010) (PubMed).

    Lee, Jadhav, Ayer, Rojas, Hyong, Lekic, Stier, Martin, Zhang: "The antioxidant effects of melatonin in surgical brain injury in rats." in: Acta neurochirurgica. Supplement, Vol. 102, pp. 367-71, (2009) (PubMed).

    Zhang, Fillmore, Zimmer: "Structural and functional analysis of domains mediating interaction between the bagpipe homologue, Nkx3.1 and serum response factor." in: Experimental biology and medicine (Maywood, N.J.), Vol. 233, Issue 3, pp. 297-309, (2008) (PubMed).

    Jiang, Yu, Zhang, Chen, Liu, Hu, Zhang: "p53 overexpression represses androgen-mediated induction of NKX3.1 in a prostate cancer cell line." in: Experimental & molecular medicine, Vol. 38, Issue 6, pp. 625-33, (2007) (PubMed).

  • 抗原

    NKX3-1 (NK3 Homeobox 1 (NKX3-1))

    别名

    NKX3A

    背景

    Nkx3.1 is a transcription factor that may play an important role in regulating proliferation of glandular epithelium and in the formation of ducts in the prostate. It has been thought to be one of the target genes of the 8p21 loss of heterozygosity, common in prostate cancer. But neither disruption of the coding region of the gene, nor mutations have been found in prostate cancer.

    分子量

    26.3 kDa

    基因ID

    4824

    UniProt

    Q99801

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus
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