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c-MYC 抗体

This anti-c-MYC antibody is a 小鼠 单克隆 antibody detecting c-MYC in ELISA. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN969300
发货至: 中国

Quick Overview for c-MYC 抗体 (ABIN969300)

抗原

See all c-MYC (MYC) 抗体
c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

适用

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宿主

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小鼠

克隆类型

  • 267
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单克隆

标记

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This c-MYC antibody is un-conjugated

应用范围

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ELISA

克隆位点

7E10
  • 原理

    MYC Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human MYC expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Fang, Liu, Wu, Liu, Pan, Li: "Upregulation of long noncoding RNA CCAT1-L promotes epithelial-mesenchymal transition in gastric adenocarcinoma." in: OncoTargets and therapy, Vol. 11, pp. 5647-5655, (2018) (PubMed).

    Zhang, Zeng, Jiao, Li, Liu, Zhang, Yang: "AA28-67 domain within MyD88 suppresses c-myc activity and expression to regulate differentiation and function of dendritic cells." in: Clinical immunology (Orlando, Fla.), Vol. 133, Issue 3, pp. 324-32, (2009) (PubMed).

    Lal, Navarro, Maher, Maliszewski, Yan, ODay, Chowdhury, Dykxhoorn, Tsai, Hofmann, Becker, Gorospe, Hide, Lieberman: "miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements." in: Molecular cell, Vol. 35, Issue 5, pp. 610-25, (2009) (PubMed).

  • 抗原

    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

    别名

    MYC

    背景

    The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. (provided by RefSeq).

    分子量

    49 kDa

    UniProt

    P01106

    途径

    p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
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