MAPK11 抗体 (AA 251-363)
Quick Overview for MAPK11 抗体 (AA 251-363) (ABIN969276)
抗原
See all MAPK11 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 251-363
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原理
- MAPK11 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of MAPK11 (aa251-363) expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Generation and characterization of p38beta (MAPK11) gene-targeted mice." in: Molecular and cellular biology, Vol. 25, Issue 23, pp. 10454-64, (2005) (PubMed).
: "Epidermal growth factor stimulation of trophoblast differentiation requires MAPK11/14 (p38 MAP kinase) activation." in: Biology of reproduction, Vol. 73, Issue 6, pp. 1282-8, (2005) (PubMed).
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: "Generation and characterization of p38beta (MAPK11) gene-targeted mice." in: Molecular and cellular biology, Vol. 25, Issue 23, pp. 10454-64, (2005) (PubMed).
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- MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))
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别名
- MAPK11
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背景
- Mitogen-activated protein kinase 11.The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.
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UniProt
- Q15759
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途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Response to Water Deprivation, Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Hepatitis C, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins
抗原
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