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Lp(a) 抗体

Cited in 2+ publications. The 小鼠 单克隆 anti-Lp(a) antibody (Clone 8F6A9) (ABIN969261) specifically detects Lp(a) in ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN969261
发货至: 中国
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Quick Overview for Lp(a) 抗体 (ABIN969261)

抗原

Lp(a) (Lipoprotein (Lp(a)))

适用

  • 28
  • 1

宿主

  • 14
  • 11
  • 3
小鼠

克隆类型

  • 16
  • 12
单克隆

标记

  • 12
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Lp(a) antibody is un-conjugated

应用范围

  • 9
  • 8
  • 8
  • 5
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (IHC)

克隆位点

8F6A9
  • 原理

    LPA Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of LPA (1823-2013) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Ranga, Kalra, Tandon, Gambhir, Mehrotra: "Effect of aspirin on lipoprotein(a) in patients with ischemic stroke." in: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, Vol. 16, Issue 5, pp. 220-4, (2007) (PubMed).

    Catalano, Cortelazzo, Yilmaz, Perilli, Carzaniga, Emanuele: "The LPA gene C93T polymorphism influences plasma lipoprotein(a) levels and is independently associated with susceptibility to peripheral arterial disease." in: Clinica chimica acta; international journal of clinical chemistry, Vol. 387, Issue 1-2, pp. 109-12, (2007) (PubMed).

  • 抗原

    Lp(a) (Lipoprotein (Lp(a)))

    别名

    LPA

    背景

    LPA: lipoprotein, Lp(a). Apo(a) is the main constituent of lipoprotein(a) (lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1.Lp(a) may be a ligand for megalin/gp 330.Apo(a) is known to be proteolytically cleaved, leading to the formation of the so-called mini-lp(a).Apo(a) fragments accumulate in atherosclerotic lesions,where they may promote thrombogenesis.O-glycosylation may limit the extent of proteolytic fragmentation.

    UniProt

    P08519
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