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KRT15 抗体

This anti-KRT15 antibody is a 小鼠 单克隆 antibody detecting KRT15 in IHC, FACS, ELISA 和 ICC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969250
发货至: 中国

Quick Overview for KRT15 抗体 (ABIN969250)

抗原

See all KRT15 抗体
KRT15 (Keratin 15 (KRT15))

适用

  • 154
  • 48
  • 28
  • 27
  • 2

宿主

  • 88
  • 71
  • 2
小鼠

克隆类型

  • 95
  • 66
单克隆

标记

  • 63
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  • 1
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  • 1
  • 1
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This KRT15 antibody is un-conjugated

应用范围

  • 92
  • 90
  • 62
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  • 43
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  • 15
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Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)

克隆位点

6E7
  • 原理

    KRT15 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of KRT15 expressed in E. Coli.

    亚型

    IgG2a
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Radoja, Stojadinovic, Waseem, Tomic-Canic, Milisavljevic, Teebor, Blumenberg: "Thyroid hormones and gamma interferon specifically increase K15 keratin gene transcription." in: Molecular and cellular biology, Vol. 24, Issue 8, pp. 3168-79, (2004) (PubMed).

    Werner, Munz: "Suppression of keratin 15 expression by transforming growth factor beta in vitro and by cutaneous injury in vivo." in: Experimental cell research, Vol. 254, Issue 1, pp. 80-90, (2000) (PubMed).

  • 抗原

    KRT15 (Keratin 15 (KRT15))

    别名

    KRT15

    背景

    The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 15 is a type I keratin without a defined type II partner. Keratin 15 is expressed primarily in the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. Expression of keratin 15 is downregulated in some hyperproliferating situations, such as psoriasis and hypertrophic scars. Because keratinocytes in psoriasis and hypertrophic scars are activated, it is suggested that keratin 15 expression is not compatible with keratinocyte activation and the keratin 15 gene is downregulated to maintain the activated phenotype.

    分子量

    49 kDa

    基因ID

    3866

    UniProt

    P19012
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