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KRT15 抗体

The 小鼠 单克隆 anti-KRT15 antibody (Clone KRT15-2554) (ABIN6939912) specifically detects KRT15 in IHC 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN6939912
发货至: 中国
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Quick Overview for KRT15 抗体 (ABIN6939912)

抗原

See all KRT15 抗体
KRT15 (Keratin 15 (KRT15))

适用

  • 156
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宿主

  • 95
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  • 2
小鼠

克隆类型

  • 99
  • 62
单克隆

标记

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This KRT15 antibody is un-conjugated

应用范围

  • 95
  • 89
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  • 15
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Immunohistochemistry (IHC), Flow Cytometry (FACS)

克隆位点

KRT15-2554
  • 原理

    Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) Antibody

    特异性

    Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins.

    纯化方法

    200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant full-length human KRT15 protein

    亚型

    IgG2b, kappa
  • 应用备注

    Positive Control: HeLa, A431 cells. Skin, Colon or Prostate.

    Known Application: Flow Cytometry (1-2 μg/million cells),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    KRT15 (Keratin 15 (KRT15))

    别名

    KRT15

    背景

    CK15, Cytokeratin 15, K1CO, Ka15, Keratin 15 basic, Keratin 15 beta, Keratin complex 1 acidic gene 15, Keratin type I cytoskeletal 15, KRT15, KRTB, KRTL15, Type I cytoskeletal 15, Type I keratin Ka15

    A431 cells. Skin, Colon or Prostate., HeLa

    分子量

    52kDa

    基因ID

    3866, 654570

    UniProt

    P19012
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