KLHL25 抗体
Quick Overview for KLHL25 抗体 (ABIN969248)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- KLHL25 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human KLHL25 expressed in E. Coli.
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亚型
- IgG2b
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study." in: BMC medical genetics, Vol. 8 Suppl 1, pp. S13, (2007) (PubMed).
: "From ORFeome to biology: a functional genomics pipeline." in: Genome research, Vol. 14, Issue 10B, pp. 2136-44, (2004) (PubMed).
: "
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Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study." in: BMC medical genetics, Vol. 8 Suppl 1, pp. S13, (2007) (PubMed).
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- KLHL25 (Kelch-Like 25 (KLHL25))
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别名
- KLHL25
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背景
- KLHL25 (ectoderm-neural cortex protein 2, ENC2) is a cytoplasmic protein that contains six Kelch regions and a single BTB (POZ) domain. KLHL25 is highly homologus to another Kelch-like protein, ENC1, and it is believed to operate in a manner similar to other Kelch-domain containing proteins. Kelch-domain repeat containing proteins often act as modifiers of Actin fibers. Expressed early in embryogenesis, ENC1 helps to mediate neuronal process formation. It also appears to have a role in neural crest cell differentiation. KLHL25 likely functions as a substrate specific adapter for protein ubiquitinating complexes. KLHL25 is expressed in most tissues with highest expression in brain and liver.
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分子量
- 65 kDa
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UniProt
- Q9H0H3
抗原
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