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JAK2 抗体 (AA 745-955)

This anti-JAK2 antibody is a 小鼠 单克隆 antibody detecting JAK2 in WB 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN969223
发货至: 中国

Quick Overview for JAK2 抗体 (AA 745-955) (ABIN969223)

抗原

See all JAK2 抗体
JAK2 (Janus Kinase 2 (JAK2))

适用

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  • 1

宿主

  • 164
  • 4
  • 1
小鼠

克隆类型

  • 149
  • 20
单克隆

标记

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This JAK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

1C1
  • 抗原表位

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    AA 745-955

    原理

    JAK2 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of JAK2(745-955aa) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Hermanns, Radtke, Haan, Schmitz-Van de Leur, Tavernier, Heinrich, Behrmann: "Contributions of leukemia inhibitory factor receptor and oncostatin M receptor to signal transduction in heterodimeric complexes with glycoprotein 130." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 12, pp. 6651-8, (2000) (PubMed).

  • 抗原

    JAK2 (Janus Kinase 2 (JAK2))

    别名

    JAK2

    背景

    This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

    分子量

    130.6 kDa

    基因ID

    3717

    UniProt

    O60674

    途径

    JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
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